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位置: 首页> 品牌> Sigma-Aldrich> 16:0-5 Doxyl PC

16:0-5 Doxyl PC

品牌
Avanti
CAS
188004-24-2
货号
810601P
规格纯度
1-palmitoyl-2-stearoyl-(5-doxyl)-sn-glycero-3-phosphocholine, powder
价格
7080.17 *本价格含增值税费
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半岛bd体育手机客户端 名称:
188004-24-2
16:0-5 Doxyl PC
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Phosphatidylcholine (PC), a strong bilayer-forming lipid is the most common phospholipid in mammalian membranes. The excretory and secretory products of helminths has a small hapten-like portion called phosphorylcholine (PC). The 5thcarbon of thesn-2 stearic acid chain of 1-palmitoyl-2-stearoyl-(5-doxyl)-sn-glycero-3-phosphocholine analog has a Doxyl PC, a spin probe attached to it covalently.
Avanti′s nitroxide spin product listing is a group of compounds designed to act as membrane probes. A variety of positions down the hydrophobic chain are labeled with the nitroxide functional groups to allow probing the membrane at various depths. These compounds have been synthesized from 1-palmitoyl-2-hydroxy-sn-glycerol-3-phosphocholine with the product being purified by column chromatography. Various n-doxyl phosphocholines have been recently used as biophysical tools to elucidate membrane trafficking with phosphatidylinositol transfer proteins and as fluorescent quenchers in lipid bilayer structural studies.

应用

16:0-5 Doxyl PC may be used:

  • as a component in virus-like large unilamellar vesicles (VL LUVs) to quench 4-chloro-7-nitrobenz-2-oxa-1,3-diazole (NBD) fluorescence emission
  • in the preparation of multi-lamellar vesicles (MLVs) as a site-specific quencher to perform fluorescence quenching studies
  • in the preparation of spin-labelled multi-lamellar vesicles (MLVs)

生化/生理作用

Phosphatidylcholine (PC) lowers the levels of cholesterol and triglycerides.

包装

5 mL Clear Glass Sealed Ampule (810601P-1mg)

制备说明

Product use:To prevent aggregation, prepare water-based solutions of 2 mM stock solutions of n-DOXYL PCs and store in plastic. Dilute stock solutions to 0.03- 0.1 mM solutions for EPR studies. For liposome preparations in fluorescent quenching measurements, dissolve the doxyl lipid in 150 μl absolute ethanol for a concentration of 40.3 mM , Additional supplemental information.

基本信息

经验(实验)分子式 C46H90N2O10P
分子量 862.19
NACRES NA.25

半岛bd体育手机客户端 性质

测定 >99% (TLC)
形式 powder
包装 pkg of 1 × 1 mg (810601P-1mg)
manufacturer/tradename Avanti Polar Lipids 810601P
运输 dry ice
储存温度 ?20℃

安全信息

储存分类代码 13 - Non Combustible Solids

Sigma-Aldrich

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