16:0-10 Doxyl PC

半岛bd体育手机客户端 说明

一般描述

Phosphocholine is considered as a precursor molecule. It is formed during the breakdown of phosphatidylcholine metabolism. 10-Doxyl is a spin label probe.
Avanti′s nitroxide spin product listing is a group of compounds designed to act as membrane probes. A variety of positions down the hydrophobic chain are labeled with the nitroxide functional groups to allow probing the membrane at various depths. These compounds have been synthesized from 1-palmitoyl-2-hydroxy-sn-glycerol-3-phosphocholine with the product being purified by column chromatography. Various n-doxyl phosphocholines have been recently used as biophysical tools to elucidate membrane trafficking with phosphatidylinositol transfer proteins and as fluorescent quenchers in lipid bilayer structural studies.

应用

16:0-10 Doxyl PC may be used:

• in vesicles for quenching PT-(1–46)F4W fluorescence
• as vesicle component for tryptophan based fluorescence emission studies
• to probe the oxygen and Ni[II] ethylenediaminediacetic acid (NiEdda) accessibilities inside liposomes

生化/生理作用

Phosphatidylcholine (PC) functions as a surfactant within the mucus to form a hydrophobic surface to inhibit bacterial penetrance.

包装

5 mL Clear Glass Sealed Ampule (810603P-1mg)

制备说明

Product use:To prevent aggregation, prepare water-based solutions of 2 mM stock solutions of n-DOXYL PCs and store in plastic. Dilute stock solutions to 0.03- 0.1 mM solutions for EPR studies. For liposome preparations in fluorescent quenching measurements, dissolve the doxyl lipid in 150 μl absolute ethanol for a concentration of 40.3 mM , Additional supplemental information.

基本信息

经验(实验)分子式	C46H90N2O10P
分子量	862.19
NACRES	NA.25

半岛bd体育手机客户端 性质

测定	>99% (TLC)
形式	powder
包装	pkg of 1 × 1 mg (810603P-1mg)
manufacturer/tradename	Avanti Polar Lipids 810603P
运输	dry ice
储存温度	?20℃

安全信息

储存分类代码

13 - Non Combustible Solids