半岛bd体育手机客户端 说明
应用
Pipamperone dihydrochloride may be used:
包装
100 mg in poly bottle
生化/生理作用
Pipamperone, a butyrophenone derivative is a pharmacological chaperone and is a membrane-permeable dopamine receptor D4 (DRD4) antagonist. The affinity of pipamperone is higher for DRD4 and 5-hydroxytryptamine 2A receptor (5-HT2A) in comparison with DRD2. It may be useful therapeutic in treating behavioral disorders and psychomotor agitation symptoms.
D2dopamine receptor antagonist; 5-HT2serotonin receptor antagonist; antipsychotic.
特点和优势
This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
基本信息
经验(实验)分子式 | C21H30N3O2F · 2HCl |
分子量 | 448.40 |
EC 号 | 219-507-5 |
MDL编号 | MFCD00242980 |
PubChem化学物质编号 | 24724576 |
NACRES | NA.77 |
半岛bd体育手机客户端 性质
质量水平 | 100 |
测定 | ~99% (HPLC) |
形式 | powder |
颜色 | white |
溶解性 | H2O: >2.0 mg/mL |
创始人 | Johnson & Johnson |
SMILES string | Cl[H].Cl[H].NC(=O)C1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)N3CCCCC3 |
InChI | 1S/C21H30FN3O2.2ClH/c22-18-8-6-17(7-9-18)19(26)5-4-12-24-15-10-21(11-16-24,20(23)27)25-13-2-1-3-14-25;;/h6-9H,1-5,10-16H2,(H2,23,27);2*1H |
InChI key | BMXXSXQVMCXGJM-UHFFFAOYSA-N |
安全信息
象形图 | |
警示用语: | Warning |
危险声明 | H302 |
危险分类 | Acute Tox. 4 Oral |
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 1 |
个人防护装备 | dust mask type N95 (US), Eyeshields, Gloves |
Sigma-Aldrich