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位置: 首页> 品牌> Sigma-Aldrich> 1′-[4-(4-Fluorophenyl)-4-oxobutyl]-[1,4′-bipiperidine]-4′-carboxamide dihydrochloride

Pipamperone dihydrochloride

1′-[4-(4-Fluorophenyl)-4-oxobutyl]-[1,4′-bipiperidine]-4′-carboxamide dihydrochloride

品牌
Sigma-Aldrich
CAS
2448-68-2
货号
P3246
规格纯度
~99% (HPLC), powder
价格
2521.28 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
2448-68-2
Pipamperone dihydrochloride
R4050
1′-[4-(4-Fluorophenyl)-4-oxobutyl]-[1,4′-bipiperidine]-4′-carboxamide dihydrochloride
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

应用

Pipamperone dihydrochloride may be used:

  • as an internal standard in liquid chromatography with coulometric detection
  • as an antipsychotic drugs to test its interaction with human ether-a-go-go-related gene (hERG) channel
  • as an internal standard to spike human colostrum samples for reversed phase liquid chromatography- ultraviolet (LC-UV) analysis

包装

100 mg in poly bottle

生化/生理作用

Pipamperone, a butyrophenone derivative is a pharmacological chaperone and is a membrane-permeable dopamine receptor D4 (DRD4) antagonist. The affinity of pipamperone is higher for DRD4 and 5-hydroxytryptamine 2A receptor (5-HT2A) in comparison with DRD2. It may be useful therapeutic in treating behavioral disorders and psychomotor agitation symptoms.
D2dopamine receptor antagonist; 5-HT2serotonin receptor antagonist; antipsychotic.

特点和优势

This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

基本信息

经验(实验)分子式 C21H30N3O2F · 2HCl
分子量 448.40
EC 号 219-507-5
MDL编号 MFCD00242980
PubChem化学物质编号 24724576
NACRES NA.77

半岛bd体育手机客户端 性质

质量水平 100
测定 ~99% (HPLC)
形式 powder
颜色 white
溶解性 H2O: >2.0 mg/mL
创始人 Johnson & Johnson
SMILES string Cl[H].Cl[H].NC(=O)C1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)N3CCCCC3
InChI 1S/C21H30FN3O2.2ClH/c22-18-8-6-17(7-9-18)19(26)5-4-12-24-15-10-21(11-16-24,20(23)27)25-13-2-1-3-14-25;;/h6-9H,1-5,10-16H2,(H2,23,27);2*1H
InChI key BMXXSXQVMCXGJM-UHFFFAOYSA-N

安全信息

象形图 GHS07
警示用语: Warning
危险声明 H302
危险分类 Acute Tox. 4 Oral
储存分类代码 13 - Non Combustible Solids
WGK WGK 1
个人防护装备 dust mask type N95 (US), Eyeshields, Gloves

Sigma-Aldrich

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