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Penfluridol

五氟利多

品牌
Sigma-Aldrich
CAS
26864-56-2
货号
P3371
规格纯度
≥97% (HPLC), powder
价格
2048.25 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
- +
半岛bd体育手机客户端 名称:
26864-56-2
Penfluridol
R16341
1-[4,4-Bis(4-fluorophenyl)butyl]-4-[4-chloro-3(trifluoromethyl)phenyl]-4-piperidinol
五氟利多
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

应用

Penfluridol has been used as an antipsychotic agent:

  • to study its antimetastatic effect on triple-negative breast cancer cells
  • to study its effects on the growth of glioblastoma cell lines,
  • to study its effects on the vascular endothelial growth factor (VEGF)-induced angiogenesis in human umbilical vein endothelial cells (HUVECs)

包装

50 mg in glass bottle

生化/生理作用

Penfluridol is studied in the treatment of schizophrenia, Tourette syndrome and acute psychosis. It also exhibits anticancer activity.
T-type Ca2+channel blocker; antipsychotic

特点和优势

This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

基本信息

经验(实验)分子式 C28H27ClF5NO
分子量 523.97
EC 号 248-074-5
MDL编号 MFCD00866714
PubChem化学物质编号 329820171
NACRES NA.77

半岛bd体育手机客户端 性质

质量水平 100
测定 ≥97% (HPLC)
形式 powder
颜色 white
溶解性 DMSO: >20 mg/mL
H2O: insoluble
创始人 Johnson & Johnson
储存温度 2-8℃
SMILES string OC1(CCN(CCCC(c2ccc(F)cc2)c3ccc(F)cc3)CC1)c4ccc(Cl)c(c4)C(F)(F)F
InChI 1S/C28H27ClF5NO/c29-26-12-7-21(18-25(26)28(32,33)34)27(36)13-16-35(17-14-27)15-1-2-24(19-3-8-22(30)9-4-19)20-5-10-23(31)11-6-20/h3-12,18,24,36H,1-2,13-17H2
InChI key MDLAAYDRRZXJIF-UHFFFAOYSA-N

安全信息

象形图 GHS06
警示用语: Danger
危险声明 H301
预防措施声明 P301 + P310
危险分类 Acute Tox. 3 Oral
储存分类代码 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable
个人防护装备 Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

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