18:0 PA

半岛bd体育手机客户端 说明

一般描述

Phosphatidic acid (PA) has two fatty acids and one phosphate group attached to a glycerol backbone. The two fatty acids are present at positionsn-1 andsn-2 of the C-atoms and the phosphate group is present in thesn-3 position of the C-atom.

应用

18:0 PA may be used:

• as a component in the bilayer to study its vesiculation ability on different coat protein I (COPI) fission factor
• to study its effects on intracellular Ca²⁺concentration ([Ca^2+]i) in C6 rat glioma and L2071 mouse fibroblast cells
• to study its effects on phosphorylation of cytochrome b(558) alpha chain (p22phox)

生化/生理作用

Phosphatidic acid (PA) acts as a biosynthetic precursor for the production of membrane glycerophospholipid and triacylglycerol. It participates in the modulation of mammalian target of rapamycin (mTOR) pathway. It may also participate in membrane trafficking, specifically in membrane fusion and fission.

包装

20 mL Clear Glass Screw Cap Vial (830865P-500mg)
5 mL Amber Glass Screw Cap Vial (830865P-25mg)

基本信息

经验(实验)分子式	C39H76O8PNa
分子量	726.98
NACRES	NA.25

半岛bd体育手机客户端 性质

测定	>99% (TLC)
形式	powder
包装	pkg of 1 × 25 mg (830865P-25mg) pkg of 1 × 500 mg (830865P-500mg)
manufacturer/tradename	Avanti Polar Lipids 830865P
运输	dry ice
储存温度	?20℃

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable