Sphinganine (d18:0)

半岛bd体育手机客户端 说明

一般描述

Sphinganine (d18:0) is a substrate for the enzyme ceramide desaturase. It is synthesized indirectly due to the interconversion of supplemented glycine to serine. Sphinganine (d18:0) is catabolized to ceramide.

应用

Sphinganine (d18:0) has been used:

• as a standard in liquid chromatography tandem mass spectrophotometry for the quantification of epidermal ceramides
• as a medium supplement to test its effect on growth of yeast cells
• in the preparation of bovine serum albumin lipid complex to investigate its effect on non-lysosomal - glucosylceramidase β2 (GBA2) inhibition

生化/生理作用

Sphinganine (d18:0) levels are not altered in hereditary sensory neuropathy type 1 cells. Accumulation of d18:0 is observed in tumor hypoxia. It is useful as a biomarker for studying microbial diversity.

包装

5 mL Amber Glass Screw Cap Vial (860498P-25mg)
5 mL Amber Glass Screw Cap Vial (860498P-100mg)
5 mL Amber Glass Screw Cap Vial (860498P-10mg)

基本信息

经验(实验)分子式	C18H39NO2
分子量	301.51
NACRES	NA.25

半岛bd体育手机客户端 性质

形式	powder
包装	pkg of 1 × 10 mg (860498P-10mg) pkg of 1 × 100 mg (860498P-100mg) pkg of 1 × 25 mg (860498P-25mg)
manufacturer/tradename	Avanti Polar Lipids 860498P
运输	dry ice
储存温度	?20℃
SMILES string	OC[C@@](N)([H])[C@]([H])(O)CCCCCCCCCCCCCCC
InChI	1S/C18H39NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)17(19)16-20/h17-18,20-21H,2-16,19H2,1H3/t17-,18+/m0/s1
InChI key	OTKJDMGTUTTYMP-ZWKOTPCHSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable