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位置: 首页> 品牌> Sigma-Aldrich> Alantolactone

Alantolactone

品牌
Sigma-Aldrich
CAS
546-43-0
货号
SML0415
规格纯度
≥98% (HPLC)
价格
1032.8 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
- +
半岛bd体育手机客户端 名称:
546-43-0
Alantolactone
Eupatal
NSC 333843
(+)-Alantolactone.
3aR,5S,8aR,9aR)-3a,5,6,7,8,8a,9,9a-Octahydro-5,8a-dimethyl-3-methylene-naphtho[2,3-b]furan-2(3H)-one
Elecampane camphor
NSC 93131
Inula camphor
Alant camphor
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Alantolactone is a compound produced by Inula helenium. Alantolactone has antibacterial, antifungal, anti-inflammatory and anticancer properties. It suppresses signal transducer and activator of transcription 3 (STAT3) activation in liver and breast cancer cells. Alantolactone induces apoptosis in A549 lung cancer cells.

应用

Alantolactone has been used:

  • in cell viability assay
  • to examine the percentage of multicentrosomal mitosis in low and high passage human embryonic stem cells (hESC)
  • in assessment of degranulation

包装

5, 25 mg in glass bottle

生化/生理作用

Alantolactone is a sesquiterpene lactone disrupts the Cripto-1/ActRII complexes, resulting in an induction of activin/SMAD3 signaling. Alantolactone inhibits proliferation in cancer cells with no affect on normal cells.

基本信息

经验(实验)分子式 C15H20O2
分子量 232.32
EC 号 208-899-3
MDL编号 MFCD00274568
PubChem化学物质编号 329825410
NACRES NA.77

半岛bd体育手机客户端 性质

质量水平 100
测定 ≥98% (HPLC)
形式 powder
储存条件 desiccated
protect from light
颜色 white to beige
溶解性 DMSO: 15 mg/mL (clear solution)
储存温度 ?20℃
SMILES string C[C@H]1CCC[C@]2(C)C[C@H]3OC(=O)C(=C)[C@H]3C=C12
InChI 1S/C15H20O2/c1-9-5-4-6-15(3)8-13-11(7-12(9)15)10(2)14(16)17-13/h7,9,11,13H,2,4-6,8H2,1,3H3/t9-,11+,13+,15+/m0/s1
InChI key PXOYOCNNSUAQNS-AGNJHWRGSA-N

安全信息

象形图 GHS07
警示用语: Warning
危险声明 H317
预防措施声明 P261 - P272 - P280 - P333 + P313 - P362 + P364 - P501
危险分类 Skin Sens. 1
储存分类代码 13 - Non Combustible Solids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

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