半岛bd体育手机客户端 说明
一般描述
During development, neuropilin-1 (NRP-1) is expressed in arteries. It is also a co-receptor of semaphorin-3a.
特异性
Shows no cross-reactivity with recombinant rat neuropilin-2.
免疫原
purified, NS0-derived, recombinant rat neuropilin-1.
生化/生理作用
Neuropilin-1 (NRP-1) has been shown to play an important role in vascular and neural functions. Neuropilin 1 (Nrp1) acts as a coreceptor for VEGF receptor 2 (VEGFR2) and increases the binding of VEGF165 to VEGFR2- and VEGF165-mediated chemotaxis. In transgenic mice, Nrp1 is implicated in embryonic vascular development. Elevated expression of the gene leads to the formation of excess capillaries and haemorrhaging.
外形
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline.
基本信息
| MDL编号 | MFCD02097027 |
| NACRES | NA.41 |
半岛bd体育手机客户端 性质
| 质量水平 | 100 |
| 生物来源 | mouse |
| 偶联物 | unconjugated |
| 抗体形式 | purified immunoglobulin |
| antibody product type | primary antibodies |
| 克隆 | 130603, monoclonal |
| 形式 | lyophilized powder |
| species reactivity | rat |
| technique(s) | indirect ELISA: 0.5-1 μg/mL using rat Neuropilin-1 |
| 同位素/亚型 | IgG2b |
| UniProt登记号 | Q9QWJ9 |
| 运输 | wet ice |
| 储存温度 | ?20℃ |
| Gene Information | rat ... Nrp1(246331) |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, type N95 (US) |
Sigma-Aldrich
m.cnreagent.com
