半岛bd体育手机客户端 说明
一般描述
A cell-permeable selective inhibitor of Ca2+-calmodulin-dependent phosphodiesterase (PDE I; IC50= 4 ?M).
A cell-permeable, selective inhibitor of Ca2+-calmodulin-dependent phosphodiesterase (PDE I, IC50= 4 ?M).
包装
10 mg in Plastic ampoule
生化/生理作用
Cell permeable: yes
Primary Target
PDE 1
Product does not compete with ATP.
Reversible: no
Target IC50: 4 ?M against Ca2+-calmodulin-dependent phosphodiesterase (PDE I)
警告
Toxicity: Standard Handling (A)
重悬
Following reconstitution aliquot and freeze at -20°C. Stock solutions are stable for up to 3 months at -20°C.
其他说明
Jackson, E.K., et al. 1997.J. Cardiovasc. Pharmacol.30,798.
Ahn, H.S., et al. 1989.Biochem. Pharmacol.38,3331.
Han, P., et al. 1989.J. Biol. Chem.274,22337.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
基本信息
经验(实验)分子式 | C12H18N4O3 |
分子量 | 266.30 |
MDL编号 | MFCD00211081 |
半岛bd体育手机客户端 性质
质量水平 | 100 |
测定 | ≥98% (TLC) |
形式 | solid |
manufacturer/tradename | Calbiochem? |
储存条件 | OK to freeze |
颜色 | white |
溶解性 | ethanol: 2 mg/mL DMSO: 5 mg/mL |
运输 | ambient |
储存温度 | 10-30℃ |
InChI | 1S/C12H18N4O3/c1-7(2)5-16-10-9(11(17)15(3)12(16)18)13-8(14-10)6-19-4/h7H,5-6H2,1-4H3,(H,13,14) |
InChI key | NBLBCGUCPBXKOV-UHFFFAOYSA-N |
安全信息
储存分类代码 | 11 - Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich