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W-7, Hydrochloride-CAS 61714-27-0-Calbiochem

品牌
Sigma-Aldrich
CAS
61714-27-0
货号
681629
规格纯度
A cell-permeable and reversible calmodulin antagonist that inhibits myosin light chain kinase (IC50= 51 μM) and Ca2+-calmodulin-dependent phosphodiesterase (IC50= 28 μM).
价格
1763.65 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
61714-27-0
W-7, Hydrochloride-CAS 61714-27-0-Calbiochem
N-(6-Aminohexyl)-5-chloro-1-naphthalenesulfonamide, HCl
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

A cell-permeable and reversible calmodulin antagonist that inhibits myosin light chain kinase (IC50= 51 ?M) and Ca2+-calmodulin-dependent phosphodiesterase (IC50= 28 ?M).
A cell-permeable and reversible calmodulin antagonist that inhibits Ca2+-calmodulin-dependent phosphodiesterase (IC50= 28 ?M) and myosin light chain kinase (IC50= 51 ?M).

包装

10 mg in Plastic ampoule

生化/生理作用

Cell permeable: yes
Primary Target
Myosin light chain kinase
Product does not compete with ATP.
Reversible: yes
Target IC50: 51 ?M inhibiting myosin light chain kinase; 28 ?M inhibiting Ca2+-calmodulin-dependent phosphodiesterase

警告

Toxicity: Standard Handling (A)

其他说明

Caulfield, M.P., et al. 1991.Neurosci. Lett.125,57.
Asano, M. 1989.J. Pharmacol. Exp. Ther.251,764.
Itoh, H., and Hidaka, H. 1984.J. Biochem.96,1721.
Tanaka, T., et al. 1983.Pharmacol.26,249.
Hidaka, H. 1981.Proc. Natl. Acad. Sci. USA78,4354.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式 C16H21ClN2O2S · xHCl
分子量 340.87 (free base basis)
MDL编号 MFCD00012559

半岛bd体育手机客户端 性质

质量水平 100
测定 ≥98% (TLC)
形式 crystalline solid
manufacturer/tradename Calbiochem?
储存条件 OK to freeze
desiccated (hygroscopic)
protect from light
颜色 off-white
溶解性 DMSO: 5 mg/mL
DMF: soluble
warm ethanol: soluble
运输 ambient
储存温度 2-8℃
InChI 1S/C16H21ClN2O2S.ClH/c17-15-9-5-8-14-13(15)7-6-10-16(14)22(20,21)19-12-4-2-1-3-11-18;/h5-10,19H,1-4,11-12,18H2;1H
InChI key OMMOSRLIFSCDBL-UHFFFAOYSA-N

安全信息

储存分类代码 11 - Combustible Solids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

Sigma-Aldrich

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