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位置: 首页> 品牌> Sigma-Aldrich> Licochalcone-A, Synthetic-CAS 58749-22-7-Calbiochem

Licochalcone-A, Synthetic-CAS 58749-22-7-Calbiochem

品牌
Sigma-Aldrich
CAS
58749-22-7
货号
435800
规格纯度
An estrogenic flavonoid with anti-tumor and antiparasitic properties.
价格
1123.01 *本价格含增值税费
促销
服务
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  • 包邮
  • 增值税票
数量
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半岛bd体育手机客户端 名称:
58749-22-7
Licochalcone-A, Synthetic-CAS 58749-22-7-Calbiochem
(E)-3-[5-(1,1-Dimethyl-2-propenyl)-4-hydroxy-2-methoxyphenyl]-1-(4-hydroxyphenyl)-2-propen-1-one
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

An estrogenic flavanoid with anti-tumor and anti-parasitic properties. Shown to reduce Bcl-2 protein expression and induce apoptosis in several human cancer cell lines. Also induces cell differentiation and enhances the effect of paclitaxel and vinblastine chemotherapy. Reported to interfere with parasite mitochondrial electron transport chain and energy metabolism.
An estrogenic flavonoid with anti-tumor and antiparasitic properties. Shown to reduce Bcl-2 protein expression and induce apoptosis in several human cancer cell lines. Also induces cell differentiation, exhibits anti-tumor activity, and enhances the effect of Paclitaxel (Cat. No. 580555) and Vinblastine (Cat. No. 677175) chemotherapy. Reported to interfere with parasite mitochondrial electron transport chain and energy metabolism.

包装

10, 50 mg in Plastic ampoule
Packaged under inert gas

生化/生理作用

Primary Target
Anti-tumor and antiparasitic properties
Product does not compete with ATP.
Reversible: no
Cell permeable: no

警告

Toxicity: Harmful (C)

制备说明

Further dilute 1:10 with aqueous buffer or medium just prior to use.

重悬

Following reconstitution aliquot and freeze at -20°C. Stock solutions are stable for up to 6 months at -20°C.

其他说明

Rafi, M.M., et al. 2000.Anticancer Res.20,2653.
Zhai, L., et al. 1999.J. Antimicrob. Chemother.43,793.
Haraguchi, H., et al. 1998.Phytochemistry48,125.
Park, E.J., et al. 1998.Planta Med.64,464.
Chen, M., et al. 1994.Antimicrob. Agents Chemother.38,1470.
Chen, M., et al. 1993.Antimicrob. Agents. Chemother.37,2550.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式 C21H22O4
分子量 338.40
MDL编号 MFCD01417903

半岛bd体育手机客户端 性质

质量水平 100
测定 ≥96% (HPLC)
形式 solid
manufacturer/tradename Calbiochem?
储存条件 OK to freeze
protect from light
颜色 yellow
溶解性 DMSO: 10 mg/mL
ethanol: soluble
运输 ambient
储存温度 ?20℃
InChI 1S/C21H22O4/c1-5-21(2,3)17-12-15(20(25-4)13-19(17)24)8-11-18(23)14-6-9-16(22)10-7-14/h5-13,22,24H,1H2,2-4H3/b11-8+
InChI key KAZSKMJFUPEHHW-DHZHZOJOSA-N

安全信息

象形图 GHS07
警示用语: Warning
危险声明 H302 + H312 + H332
预防措施声明 P261 - P264 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312
危险分类 Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral
储存分类代码 11 - Combustible Solids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

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