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位置: 首页> 品牌> Sigma-Aldrich> Anti-TCR Vγ1.1 Antibody, clone 2.11

Anti-TCR Vγ1.1 Antibody, clone 2.11

品牌
Sigma-Aldrich
货号
MABF930M
规格纯度
clone 2.11, from hamster(Armenian)
价格
5016.79 *本价格含增值税费
促销
服务
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数量
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半岛bd体育手机客户端 名称:
Anti-TCR Vγ1.1 Antibody, clone 2.11
T-cell receptor gamma chain C region C10.5
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

T cell receptor (TCR) is a single-pass membrane protein that associates with CD3 to form a CD3/TCR complex. It can be a heterodimer of either alpha and beta chains or gamma and delta chains. CD3/RCR complex plays major role in antigen recognition and activation of T cells. The V gamma 1 gene almost exclusively rearranges to the J gamma 4-C gamma 4 gene. V-gamma 1- J gamma 4-C gamma 4 expressing cells form a major population of gamma/delta T cells in thymus and peripheral lymphoid organs in adult mice. However, during early development they are present in lower numbers. This antibody (clone 2.11) recognizes the V gamma 1.1 chain of the heterodimeric gamma/delta T-cell receptor, but does react with TCR alpha/beta bearing cells.

特异性

Clone 2.11 detects T-cell receptor gamma chain C region C10.5 in lymphocytes.

免疫原

Irradiated TCR gamma/delta expressing T3 .13.1 hybridoma cells.

应用

Anti-TCR V 1.1, clone 2.11, Cat. No. MABF930, is an armenian hamster monoclonal antibody that detects T-cell receptor gamma chain C region C10.5. and has been tested for use Flow Cytometry, and Immunoprecipitation.
Flow Cytometry Analysis: A representative lot detected TCR V gamma 1.1 in Flow Cytometry applications (Pereira, P., et. al. (1995). J Exp Med. 182(6):1921-30; Pereira, P., et. al. (2004). J Immunol. 173(5):3261-70).

Flow Cytometry Analysis: A 1:500 dilution from a representative lot detected TCR V gamma 1.1 in Lymphocytes isolated from TcrdH2BeGFP reporter mice (Courtesy of Dr rer. nat. Inga Sandrock, Hannover Medical School, Germany).

Immunoprecipitation Analysis: A representative lot detected TCR V gamma 1.1 in Immunoprecipitation applications (Pereira, P., et. al. (1995). J Exp Med. 182(6):1921-30).

Research Category
Inflammation & Immunology

质量

Identity Confirmation by Isotyping Test.

Isotyping Analysis: The identity of this monoclonal antibody is confirmed by isotyping test to be mouse IgG.

目标描述

19.10 kDa calculated.

外形

Protein G purified
Format: Purified
Purified armenian hamster monoclonal antibody IgG in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

其他说明

Concentration: Please refer to lot specific datasheet.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss 32160702

半岛bd体育手机客户端 性质

生物来源 hamster (Armenian)
质量水平 100
抗体形式 purified immunoglobulin
antibody product type primary antibodies
克隆 2.11, monoclonal
species reactivity mouse
包装 antibody small pack of 25 μg
technique(s) flow cytometry: suitable
immunoprecipitation (IP): suitable
同位素/亚型 IgGκ
UniProt登记号 P01853

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

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