Meloxicam sodium salt hydrate

品牌

Sigma-Aldrich

CAS

71125-39-8

货号

M3935

包装型号

100 MG, ≥98% (HPLC)

规格纯度

≥98% (HPLC)

价格

2684.1 元 *本价格含增值税费

促销

数量

- +

半岛bd体育手机客户端名称：

71125-39-8
Meloxicam sodium salt hydrate
4-Hydroxy-2-methyl-N-(5-methyl-2-thiazolyl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide sodium hydrate
Metacam sodium salt hydrate
UH-AC 62XX sodium salt hydrate
Mobec sodium salt hydrate

半岛bd体育手机客户端介绍：

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应用

Meloxicam sodium salt hydrate has been used:

as a cyclooxygenase-2 (COX-2) inhibitor in solid Ehrlich tumor
as an alternative to diclofenac nonsteroidal anti-inflammatory drugs (NSAID) to treat vultures
as a reference standard in liquid chromatography electrospray ionisation mass spectrometry (LC-ESI/MS)
to test its effect on prostaglandin (PGE2) production in lipopolysaccharide (LPS)-induced COX-2 protein expression in RAW246.7 cells

包装

100 mg in glass bottle

生化/生理作用

Meloxicam, a member of the oxicam family, is a non-steroidal anti-inflammatory drug (NSAID). It is synthesized from piroxicam with aryl and the pyridyl ring substitution. Meloxicam is a cyclooxygenase-2 (COX-2) inhibitor, it may be useful in treating inflammation and pain. Meloxicam has been shown to stop thymulin-induced increas in concentration of cytokines and Nerve growth factor (NGF) in the liver of rats. Meloxicam also suppresses tumor growth and may be capable of antagonizing cachexiain vitro. It promotes apoptosis in hepatocellular carcinoma.

特点和优势

This compound was developed by Boehringer Ingelheim. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

基本信息

经验(实验)分子式	C₁₄H₁₂N₃NaO₄S₂· xH₂O
分子量	373.38 (anhydrous basis)
MDL编号	MFCD11046047
PubChem化学物质编号	24278802
NACRES	NA.77

半岛bd体育手机客户端性质

测定	≥98% (HPLC)
形式	powder
颜色	light yellow to dark yellow
溶解性	DMSO: 5 mg/mL, clear
创始人	Boehringer Ingelheim
储存温度	room temp
SMILES string	O.[Na+].CN1C(C(=O)Nc2ncc(C)s2)=C([O-])c3ccccc3S1(=O)=O
InChI	1S/C14H13N3O4S2.Na.H2O/c1-8-7-15-14(22-8)16-13(19)11-12(18)9-5-3-4-6-10(9)23(20,21)17(11)2;;/h3-7,18H,1-2H3,(H,15,16,19);;1H2/q;+1;/p-1
InChI key	IZBZAOZGNNQKPJ-UHFFFAOYSA-M
Gene Information	human ... PTGS2(5743)

安全信息

象形图
警示用语：	Danger
危险声明	H301 - H315 - H319 - H335
预防措施声明	P301 + P310 + P330 - P302 + P352 - P305 + P351 + P338
危险分类	Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官	Respiratory system
储存分类代码	6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable