Anti-MOG (N-terminal) antibody produced in rabbit

半岛bd体育手机客户端 说明

一般描述

Myelin/oligodendrocyte glycoprotein (MOG) is an integral membrane glycoprotein belonging to the large immunoglobulin superfamily. It is a 26-28kDa glycoprotein localized on chromosome 6p21.3. It consists of an extracellular immunoglobulin-like domain and two hydrophobic regions. It is expressed on the surface of myelinating oligodendrocytes and external lamellae of myelin sheaths in the central nervous system.

免疫原

synthetic peptide corresponding to amino acids 84-100 located near the N-terminal region of human MOGα1 isoform, conjugated to KLH. This sequence is identical in human MOGα1-3 and MOGβ1-4 isoforms, deleted in MOGα4 isoform, and identical in rat, mouse, and bovine MOG.

应用

Anti-MOG (N-terminal) antibody produced in rabbit is suitable for western blot at a concentration of 1-2μg/mL using recombinant human MOG protein.

生化/生理作用

Myelin/oligodendrocyte glycoprotein (MOG) is a major component of the central nervous system. It is involved in several cellular processes including cellular adhesion, in the regulation of oligodendrocyte microtubule stability and facilitates the interactions between myelin and the immune system. It has been reported that MOG may be involved in the completion and/or maintenance of the myelin sheath, and in cell-cell communication. It has also been observed that mutation or polymorphisms in MOG gene could cause multiple sclerosis.

外形

0.01M 磷酸缓冲盐溶液，pH 7.4，含 15mM 叠氮化钠。

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号	MFCD08705481
NACRES	NA.41

半岛bd体育手机客户端 性质

生物来源	rabbit
质量水平	200
偶联物	unconjugated
抗体形式	affinity isolated antibody
antibody product type	primary antibodies
克隆	polyclonal
形式	buffered aqueous solution
species reactivity	human
technique(s)	western blot: 1-2 μg/mL using recombinant human MOG protein
UniProt登记号	Q16653
运输	dry ice
储存温度	?20℃
Gene Information	human ... MOG(4340)

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)