半岛bd体育手机客户端 说明

一般描述

Matrix metalloproteinase-28 (MMP-28) is expressed in normal tissues like the epidermis of the skin, brain, lungs and intestine. It possesses an activation sequence and a pro-domain. The gene encoding it is localized on human chromosome 17q11.2 and has eight exons.

特异性

By immunoblotting against the reduced protein, the antibody identifies bands at 62 kDa and 58 kDa, as well as breakdown products at 50 kDa, 48 kDa, and 46 kDa. At higher antibody concentrations, the antibody also detects a 70 kDa band in rat and mouse tissues.

免疫原

synthetic peptide corresponding to the propeptide region of human matrix metalloproteinase-28.

生化/生理作用

Matrix metalloproteinase-28 (MMP-28) may have a role in modulating matrix composition. It is an endopeptidase which degrades casein and mediates epithelial to mesenchymal transition. MMP-28 aids in progression of tumors and is overexpressed in gastric carcinomas.

外形

Solution in 0.01 M phosphate buffered saline containing 50% glycerol and 0.05% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号	MFCD04040453
NACRES	NA.41

半岛bd体育手机客户端 性质

生物来源	rabbit
质量水平	200
偶联物	unconjugated
抗体形式	affinity isolated antibody
antibody product type	primary antibodies
克隆	polyclonal
形式	buffered aqueous glycerol solution
species reactivity	human
浓度	~1 mg/mL
technique(s)	western blot: 1:1,000
UniProt登记号	Q9H239
运输	wet ice
储存温度	?20℃
Gene Information	human ... MMP28(79148)

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)