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gamma-Mangostin

γ-倒捻子素

品牌
Sigma-Aldrich
CAS
31271-07-5
货号
M6824
规格纯度
≥98% (HPLC)
价格
4854.17 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
- +
半岛bd体育手机客户端 名称:
31271-07-5
gamma-Mangostin
Normangostin
1,3,6,7-Tetrahydroxy-2,8-bis(3,3-dimethylallyl)xanthone
Demethylmangostin
γ-倒捻子素
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

The fruit hulls of mangosteen contain three major bioactive compounds namely, α-, β-, and γ-mangostin.

应用

γ-Mangostin has been used to study its inhibitory effect on Transthyretin (TTR) fibrillization, a homotetrameric protein involved in human hereditary amyloidosis.

包装

10 mg in glass bottle
50 mg in poly bottle

生化/生理作用

The xanthone derivatives, namely α-, β-, and γ-mangostin have various biological activities including antiproliferative and anti-inflammatory activity, enhancement of natural killer (NK) cell activity, and antiviral effect against human immunodeficiency virus (HIV). γ-Mangostin is also reported to inhibit cyclooxygenase (COX-2) activity and NO production, which in turn reduces the level of prostaglandin E2. It is found to induce cell death in human colon cancer cells.
Xanthone derivative isolated from the mangosteen hull (Garcinia mangostana). Exhibits antioxidant and anticancer properties. Mangosteen xanthones inhibit inflammation in human adipocytes which is important in understanding obesity-associated inflammation and the development of insulin resistance.

基本信息

经验(实验)分子式 C23H24O6
分子量 396.43
MDL编号 MFCD00951752
NACRES NA.25

半岛bd体育手机客户端 性质

质量水平 100
测定 ≥98% (HPLC)
形式 powder
颜色 off-white to yellow
溶解性 methanol: 1 mg/mL, colorless to yellow
储存温度 2-8℃
SMILES string OC1=CC(OC2=CC(O)=C(CC=C(C)C)C(O)=C2C3=O)=C3C(CC=C(C)C)=C1O
InChI 1S/C23H24O6/c1-11(2)5-7-13-15(24)9-18-20(22(13)27)23(28)19-14(8-6-12(3)4)21(26)16(25)10-17(19)29-18/h5-6,9-10,24-27H,7-8H2,1-4H3
InChI key VEZXFTKZUMARDU-UHFFFAOYSA-N

安全信息

象形图 GHS07
警示用语: Warning
危险声明 H302
预防措施声明 P301 + P312 + P330
危险分类 Acute Tox. 4 Oral
储存分类代码 11 - Combustible Solids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

Sigma-Aldrich

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