半岛bd体育手机客户端 说明

一般描述

Complex of N-terminal 6His-tagged, recombinant, full-length mouse p110α containing the mutation H1047R αand untagged, recombinant, full length mouse p85α.
Product Source: Coexpressed by baculovirus in Sf21 insect cells.
The H1047R substitution in p110α is associated with a number of human cancers. The residue is conserved between the human and mouse sequences. In vitro studies have shown that this mutation confers increased lipid kinase activity compared to wild type, and is able to induce oncogenic transformation.

应用

Research Category
Inflammation & Immunology

生化/生理作用

Protein Target: PI3Kα/p85α
Target Sub-Family: PI3K/PI4K

包装

Also available in 250μg size --call for pricing and availability and reference catalog number 14-787M when ordering the 250μg size.

外形

Ni²⁺/NTA-agarose

储存及稳定性

Store at -70°C from date of shipment. For maximum recovery of product, centrifuge original vial prior to removing the cap.

其他说明

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

法律信息

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss	32160405
NACRES	NA.32

半岛bd体育手机客户端 性质

质量水平	300 100
生物来源	mouse
分子量	Mw129 kDa (p110α; H1047R) Mw83.6 kDa (p85α)
manufacturer/tradename	Upstate?
technique(s)	activity assay: suitable (kinase)
NCBI登记号	NM_006218.2
UniProt登记号	P42336
Gene Information	mouse ... PIK3CA(18706)

安全信息

象形图
警示用语：	Warning
危险声明	H317
预防措施声明	P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
危险分类	Skin Sens. 1
储存分类代码	12 - Non Combustible Liquids
WGK	WGK 2
闪点(F)	Not applicable
闪点(C)	Not applicable