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GCN2, active

品牌
Sigma-Aldrich
货号
14-934-M
包装型号
规格纯度
价格
6898.57 *本价格含增值税费
促销
服务
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数量
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半岛bd体育手机客户端 名称:
GCN2, active
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

GCN2 (EIF2AK4) belongs to a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor-2 (EIF2S1) to downregulate protein synthesis in response to varied cellular stresses.
Product Source: N-terminal GST-tagged, recombinant, human GCN2 full length, expressed by baculovirus in Sf21 insect cells. The recombinant protein contains the amino acid substitution E556G with reference to GenPept NP_001013725. E556G is reported in GenPept CAH10626.

生化/生理作用

Target Sub-Family: STE

包装

Also available in250μgsize as catalog #14-934Mand inbulkas catalog #14-934-K.

质量

Routinely evaluated by phosphorylation of peptide RSRSRSRSRSRSRSR

外形

Purified using glutathione sepharose.
Protein in 50mM Tris/HCl pH7.5, 300mM NaCl, 0.1mM EGTA, 0.03% Brij-35, 270mM sucrose, 1mM benzamidine, 0.2mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution.

储存及稳定性

6 months at -70°C

其他说明

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

法律信息

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss 32160405
NACRES NA.32

半岛bd体育手机客户端 性质

质量水平 100
生物来源 human
分子量 Mw215 kDa
manufacturer/tradename Upstate?
technique(s) activity assay: suitable (kinase)
NCBI登记号 NP_001013725
UniProt登记号 Q9P2K8
Gene Information human ... EIF2AK4(440275)

安全信息

象形图 GHS07
警示用语: Warning
危险声明 H317
预防措施声明 P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
危险分类 Skin Sens. 1
储存分类代码 10 - Combustible liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

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