半岛bd体育手机客户端 说明

一般描述

Luotonin B is a heteroaromatic pyrroloquinazolinoquinoline alkaloid that, along with Luotonin A and E, was originally isolated from the Chinese medicinal plantPaganum nigellastrum. It is an oxidation product of Luotonin A and is converted to Luotonin E by methanol treatment.

包装

10 mg in glass bottle
50 mg in poly bottle

生化/生理作用

Luotonin compounds have antitumor activity and demonstrate cytotoxicity and inhibitory activity against human topoisomerase. For use as a topoisomerase inhibitor, a starting concentration of 25 μM is suggested. It is suggested that a dose-response curve be performed to find the inhibitor concentration most suitable for the intended assay.

重悬

Solubility is tested at 2 mg/mL in 4:1 solution of choloform and methanol. Solubility of luotonins in DMSO has been reported.

基本信息

经验(实验)分子式	C18H11N3O2
分子量	301.30
NACRES	NA.77

半岛bd体育手机客户端 性质

质量水平	200
生物来源	synthetic (organic)
测定	≥98%
形式	solid
溶解性	chloroform/methanol (4:1): 2 mg/mL, clear to slightly hazy, colorless to yellow
运输	wet ice
储存温度	?20℃
Gene Information	human ... TOP1(7150)

安全信息

象形图
警示用语：	Danger
危险声明	H301
预防措施声明	P264 - P270 - P301 + P310 - P405 - P501
危险分类	Acute Tox. 3 Oral
储存分类代码	6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable