Rat/Mouse Ghrelin (active) ELISA

半岛bd体育手机客户端 说明

一般描述

Circulating ghrelin is a multifunctional hormone secreted primarily by the stomach. Originally found as an endogenous ligand for the growth hormone secretagogue receptor, it is also an appetite-stimulating hormone in the regulation of energy homeostasis. It consists of 28 amino acids and the n-octanoylation of serine-3 position is necessary for its bioactivity. Long considered a key player in obesity, ghrelin may also play a role in maintaining the balance between insulin and glucose and the development of diabetes. The spike in insulin secretion occurring after eating usually correlates with a dip in ghrelin production. Researchers determined that in rat models of uncontrolled diabetes, food intake still suppressed ghrelin concentrations in the blood, but only approximately half as effectively as when insulin was present.

Millipore is pleased to offer a new Rat/Mouse Ghrelin (Active) ELISA kit for the quantification of active ghrelin in rat and mouse serum or plasma samples. Each kit is sufficient to measure 39 unknown samples in duplicate.

特异性

Rat/Mouse Ghrelin (Active) - 100%
Rat/Mouse "Des-Octanoyl" Ghrelin - 0%
Canine Ghrelin (Active) - 111%
Porcine Ghrelin (Active) - 98%

应用

Used to detect/quantify: Ghrelin

其他说明

Please contact Technical Service for linearity of dilution.

免责声明

For research use only. Not for use in diagnostic procedures.

基本信息

eCl@ss	32161000
NACRES	NA.32

半岛bd体育手机客户端 性质

质量水平	100
species reactivity	mouse, rat
technique(s)	ELISA: suitable
UniProt登记号	Q9EQX0 (mouse) Q9QYH7 (rat) Q9UBU3
assay range	inter-assay cv: 1-10% intra-assay cv: 0.3-7% (Serum) inter-assay cv: 1-5% intra-assay cv: 1-6% (Plasma)
detection method	colorimetric fluorometric

安全信息

象形图
警示用语：	Danger
危险声明	H290 - H302 + H332 - H311 - H315 - H317 - H319 - H335 - H411
预防措施声明	P273 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338
危险分类	Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Met. Corr. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
靶器官	Respiratory system
储存分类代码	6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK	WGK 3