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PKCζ, active, GST tagged human

品牌
Sigma-Aldrich
货号
K4018
规格纯度
PRECISIO?Kinase, recombinant, expressed in baculovirus infectedSf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
价格
4449.75 *本价格含增值税费
促销
服务
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数量
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半岛bd体育手机客户端 名称:
PKCζ, active, GST tagged human
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

生化/生理作用

PKCζ (protein kinase C ζ) is a atypical PKC and works independent of Ca2+and diacylglycerol. It is involved in MAPK (mitogen-activated protein kinase)-induced nuclear factor κ B activation. It also stabilizes DNA mismatch-repair proteins, participates in laeukemic cell differentiation, cell migration and chemotaxis. PKCζ have tumour suppressor as well as oncogenic properties. Upregulation of PKCζ causes apoptosis in ovarian carcinoma cells. On the other hand, absence of PKCζ decreases tumorigenic activity in a colon cancer mouse model.

外形

Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.2 5mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.

法律信息

PRECISIO is a registered trademark of sigma-aldrich Co. LLC

基本信息

NACRES NA.32

半岛bd体育手机客户端 性质

质量水平 200
重组 expressed in baculovirus infectedSf9 cells
半岛bd体育手机客户端 线 PRECISIO?Kinase
测定 ≥70% (SDS-PAGE)
形式 buffered aqueous glycerol solution
specific activity 97-131 nmol/min·mg
分子量 ~93 kDa
UniProt登记号 Q05513
运输 dry ice
储存温度 ?70℃
Gene Information human ... PRKCZ(5590)

安全信息

储存分类代码 10 - Combustible liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable
个人防护装备 Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Sigma-Aldrich

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