半岛bd体育手机客户端 说明
生化/生理作用
JNK1 (c-Jun N-terminal kinase 1) is a member of the MAPK (mitogen activated protein kinase) family that controls gene expression by phosphorylation of transcription factors. It is linked with apoptosis, brain development and learning ability. JNK1 also influences cell migration via phosphorylation of paxillin. JNK1 also regulates obesity and insulin resistance.
As a member of the MAP kinase family, JNK1 is known to play a role in the induction of apoptosis through various stimuli such as TNFa.JNK1 also is influences cell migration via phosphorylation of paxillin.JNK1 is also a crucial mediator of obesity and insulin resistance and a potential target for therapeutics.
外形
Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.2 5mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.
法律信息
PRECISIO is a registered trademark of sigma-aldrich Co. LLC
基本信息
| NACRES | NA.32 |
半岛bd体育手机客户端 性质
| 质量水平 | 200 |
| 重组 | expressed in baculovirus infectedSf9 cells |
| 半岛bd体育手机客户端 线 | PRECISIO?Kinase |
| 测定 | ≥90% (SDS-PAGE) |
| 形式 | buffered aqueous glycerol solution |
| specific activity | 92-124 nmol/min·mg |
| 分子量 | ~71 kDa |
| UniProt登记号 | Q91Y86 |
| 运输 | dry ice |
| 储存温度 | ?70℃ |
| Gene Information | mouse ... Mapk8(26419) |
安全信息
| 储存分类代码 | 10 - Combustible liquids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |
Sigma-Aldrich
m.cnreagent.com
