半岛bd体育手机客户端 说明
免疫原
purified,E. coli-derived recombinant mouse interleukin-1α/interleukin-1F1.
生化/生理作用
Interleukins are proinflammatory cytokines produced on cell injury or trauma. There are two closely related types of interleukins produced by the cell, IL-1α and IL-1β that are produced in response to bacterial infection or LPS. Both IL-1α and IL-1β exert their cellular effects by signaling through IL-1 receptor type 1. The effects of IL-1α are mediated by activation of NF-κB, JNK and MAPK pathways that activated the genes in response to infection and inflammation. Overproduction of IL-1α has been implicated in inflammatory disorders like rheumatoid arthritis and periodontitis.
外形
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.
基本信息
MDL编号 | MFCD00162513 |
NACRES | NA.41 |
半岛bd体育手机客户端 性质
质量水平 | 100 |
生物来源 | rat |
偶联物 | unconjugated |
抗体形式 | purified immunoglobulin |
antibody product type | primary antibodies |
克隆 | 40508, monoclonal |
形式 | lyophilized powder |
species reactivity | mouse |
technique(s) | capture ELISA: 2 μg/mL neutralization: suitable |
UniProt登记号 | P01582 |
储存温度 | ?20℃ |
Gene Information | mouse ... Il1a(16175) |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
个人防护装备 | Eyeshields, Gloves, type N95 (US) |
Sigma-Aldrich