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位置: 首页> 品牌> Sigma-Aldrich> Monoclonal Anti-Interleukin-1α/Interleukin-1F1 antibody produced in rat

Monoclonal Anti-Interleukin-1α/Interleukin-1F1 antibody produced in rat

品牌
Sigma-Aldrich
货号
I8159
规格纯度
clone 40508, purified immunoglobulin, lyophilized powder
价格
4330.86 *本价格含增值税费
促销
服务
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数量
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半岛bd体育手机客户端 名称:
Monoclonal Anti-Interleukin-1α/Interleukin-1F1 antibody produced in rat
Anti-IL1A
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

免疫原

purified,E. coli-derived recombinant mouse interleukin-1α/interleukin-1F1.

生化/生理作用

Interleukins are proinflammatory cytokines produced on cell injury or trauma. There are two closely related types of interleukins produced by the cell, IL-1α and IL-1β that are produced in response to bacterial infection or LPS. Both IL-1α and IL-1β exert their cellular effects by signaling through IL-1 receptor type 1. The effects of IL-1α are mediated by activation of NF-κB, JNK and MAPK pathways that activated the genes in response to infection and inflammation. Overproduction of IL-1α has been implicated in inflammatory disorders like rheumatoid arthritis and periodontitis.

外形

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.

基本信息

MDL编号 MFCD00162513
NACRES NA.41

半岛bd体育手机客户端 性质

质量水平 100
生物来源 rat
偶联物 unconjugated
抗体形式 purified immunoglobulin
antibody product type primary antibodies
克隆 40508, monoclonal
形式 lyophilized powder
species reactivity mouse
technique(s) capture ELISA: 2 μg/mL
neutralization: suitable
UniProt登记号 P01582
储存温度 ?20℃
Gene Information mouse ... Il1a(16175)

安全信息

储存分类代码 13 - Non Combustible Solids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable
个人防护装备 Eyeshields, Gloves, type N95 (US)

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