ITK (352-end), active, GST tagged human

半岛bd体育手机客户端 说明

一般描述

ITK (IL2-inducible T-cell kinase) is a member of the Tec family of tyrosine kinases. ITK is expressed in T-cells.

生化/生理作用

ITK (IL2-inducible T-cell kinase) is important for T-cell activation through the T-cell antigen receptor. Absence of ITK in T cells causes impairment in TCR (T cell receptor)-mediated actin polymerization, cell polarization and signaling events associated with cytoskeletal reorganization.

外形

Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.2 5mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.

法律信息

PRECISIO is a registered trademark of sigma-aldrich Co. LLC

基本信息

NACRES

NA.32

半岛bd体育手机客户端 性质

质量水平	200
重组	expressed in baculovirus infectedSf9 cells
半岛bd体育手机客户端 线	PRECISIO?Kinase
测定	≥70% (SDS-PAGE)
形式	buffered aqueous glycerol solution
specific activity	49-67 nmol/min·mg
分子量	~53 kDa
UniProt登记号	Q08881
运输	dry ice
储存温度	?70℃
Gene Information	human ... ITK(3702)

安全信息

储存分类代码	10 - Combustible liquids
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)