半岛bd体育手机客户端 说明
生化/生理作用
INSR (insulin receptor) belongs to the receptor tyrosine kinase family and is a cell surface receptor. Insulin binding to INSR results in autophosphorylation and increased catalytic activity. These events are important for downstream signalling. Insulin/INSR signaling is crucial in the central nervous system for controlling blood glucose levels, synaptic plasticity, dendritic growth, regulation of electrophysiological activity, astrocytes proliferation and neuronal cell death. Mutations in INSR are associated with hyperinsulinemic hypoglycemia syndrome.
外形
Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.2 5mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.
法律信息
PRECISIO is a registered trademark of sigma-aldrich Co. LLC
基本信息
| NACRES | NA.32 |
半岛bd体育手机客户端 性质
| 质量水平 | 200 |
| 重组 | expressed in baculovirus infectedSf9 cells |
| 半岛bd体育手机客户端 线 | PRECISIO?Kinase |
| 测定 | ≥70% (SDS-PAGE) |
| 形式 | buffered aqueous glycerol solution |
| specific activity | 2281-3086 nmol/min·mg |
| 分子量 | ~70 kDa |
| UniProt登记号 | P06213 |
| 运输 | dry ice |
| 储存温度 | ?70℃ |
| Gene Information | human ... INSR(3643) |
安全信息
| 储存分类代码 | 10 - Combustible liquids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |
Sigma-Aldrich
m.cnreagent.com
