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IGF1R (960-end), active, His tagged human

品牌
Sigma-Aldrich
货号
I0786
规格纯度
PRECISIO?Kinase, recombinant, expressed in baculovirus infectedSf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
价格
6484.55 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
- +
半岛bd体育手机客户端 名称:
IGF1R (960-end), active, His tagged human
CD221
JTK13
MGC142170
MGC142172
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

生化/生理作用

IGF1R (insulin-like growth factor 1 receptor) is a transmembrane tyrosine kinase receptor that is activated by IGF1 (insulin-like growth factor 1) as well as IGF2. IGF1R plays a key role in tumorigenesis. The IGF1R is implicated in several cancers, most notably breast cancer where it is highly overexpressed and causes disease progression and poor prognosis. In many instances, IGF1R overexpression allows cancerous cells to resist the cytotoxic properties of chemotheraputic drugs or radiotherapy.

外形

Supplied in 50 mM Sodium Phosphate, pH 7.0, with 150 mM imidazole, 0.1 mM PMSF, 0.2 mM DTT, and 25% glycerol.

法律信息

PRECISIO is a registered trademark of sigma-aldrich Co. LLC

基本信息

NACRES NA.32

半岛bd体育手机客户端 性质

质量水平 200
重组 expressed in baculovirus infectedSf9 cells
半岛bd体育手机客户端 线 PRECISIO?Kinase
测定 ≥70% (SDS-PAGE)
形式 buffered aqueous glycerol solution
specific activity 224-302 nmol/min·mg
分子量 ~53 kDa
UniProt登记号 P08069
相关疾病 cancer
运输 dry ice
储存温度 ?70℃
Gene Information human ... IGF1R(3480)

安全信息

储存分类代码 10 - Combustible liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

Sigma-Aldrich

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