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Anti-Interleukin-1α antibody produced in goat

品牌
Sigma-Aldrich
货号
I8534
规格纯度
affinity isolated antibody, lyophilized powder
价格
4330.86 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
Anti-Interleukin-1α antibody produced in goat
Anti-IL-1α
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Interleukins are proinflammatory cytokines produced on cell injury or trauma. There are two closely related types of interleukins produced by the cell, IL-1α and IL-1β that are produced by the activation of NF-κ B transcription factor in response to bacterial infection or LPS. Both IL-1α and IL-1β exert their cellular effects by signalling through IL-1 receptor type 1. A variety of cells such as macrophages, epithelial cells, fibroblasts, keratinocytes, monocytes and dendritic cells secrete IL-1α. Both IL-1α and IL-1β are important in acquired immunity, inflammation, response to infection and production of matrix metalloproteinases (MMPs). The effects of IL-1α are mediated by activation of NF-κB, JNK and MAPK pathways that activated the genes in response to infection and inflammation. Overproduction of IL-1α has been implicated in inflammatory disorders like rheumatoid arthritis and periodontitis
Anti-interleukin-1α specifically reacts with murine IL-1α.

免疫原

purified,E. coli-derived recombinant mouse interleukin-1α.

应用

Anti-interleukin 1α antibody may be used for immunoblotting at a working concentration of 0.1-0.2 μg/ml. For immunohistochemistry and immunofluorescence, a working concentration of ~15 μg/ml is recommended. It is also suitable for neutralization reactions.

外形

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.

基本信息

MDL编号 MFCD00165461
NACRES NA.41

半岛bd体育手机客户端 性质

质量水平 100
生物来源 goat
偶联物 unconjugated
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
形式 lyophilized powder
species reactivity mouse
technique(s) immunohistochemistry: 15 μg/mL
neutralization: suitable
western blot: 0.1-0.2 μg/mL
UniProt登记号 P01582
储存温度 ?20℃
Gene Information mouse ... Il1a(16175)

安全信息

储存分类代码 13 - Non Combustible Solids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable
个人防护装备 Eyeshields, Gloves, type N95 (US)

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