半岛bd体育手机客户端 说明

一般描述

Idebenone is a short-chain benzoquinone drug.

应用

Idebenone has been used:

• to treat mutant myocilin (mMYOC) cells for drug treatment assay
• to validate C2C12 secondary cell screening assay
• to treat obese mice, to test whether idebenone and CoQ10 bind directly to peroxisome proliferator-activated receptor (PPAR)LBDs, His-tagged PPARα, δ and γ LBDs

包装

25 mg in glass insert
100 mg in poly bottle

生化/生理作用

Idebenone is used in the treatment of visual impairment in adolescents and adults with Leber′s hereditary optic neuropathy (LHON). It serves as an antioxidant. It helps to guard the heart muscle against oxidative stress.
一种短链辅酶 Q 类似物，可通过介导电子从 N2 转移到氧来增强超氧化物的形成。

基本信息

经验(实验)分子式	C19H30O5
分子量	338.44
MDL编号	MFCD00274552
PubChem化学物质编号	329815386

半岛bd体育手机客户端 性质

质量水平	200
测定	≥98% (HPLC)
形式	powder
溶解性	methanol: 50 mg/mL, clear to slightly hazy
储存温度	room temp
SMILES string	O=C(C(OC)=C1OC)C(CCCCCCCCCCO)=C(C)C1=O
InChI	1S/C19H30O5/c1-14-15(12-10-8-6-4-5-7-9-11-13-20)17(22)19(24-3)18(23-2)16(14)21/h20H,4-13H2,1-3H3
InChI key	JGPMMRGNQUBGND-UHFFFAOYSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable