您好,欢迎来到半岛电竞官方网址 ! [ 登录] [ 免费注册]
半岛电竞官方网址
位置: 首页> 品牌> Sigma-Aldrich> Anti-Beta Pix, SH3 Domain Antibody

Anti-Beta Pix, SH3 Domain Antibody

品牌
Sigma-Aldrich
货号
07-1450-I
规格纯度
from rabbit, purified by affinity chromatography
价格
5688.25 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
- +
半岛bd体育手机客户端 名称:
Anti-Beta Pix, SH3 Domain Antibody
Rho guanine nucleotide exchange factor 7, Beta-Pix, COOL-1, PAK-interacting exchange factor beta, p85
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Beta-Pix (ARHGEF7, βPix, COOL) is a Rho guanine nucleotide exchange factor (GEF). Beta-Pix is a p21-activated protein kinase (PAK)-interacting exchange factor (Pix, COOL, p85SPR) that has been identified as a putative guanine nucleotide exchange factor (GEF) for Rac/Cdc42. The variants of Beta-Pix isoforms exhibit different tissue distributions. Beta-Pix-a is expressed ubiquitously in all the tissues examined, and other isoforms are expressed mainly in the central nervous system. PAK, a Ser/Thr kinase, is an important mediator of Rho family activity interacts with Beta-Pix at the SH3 domain of Beta-Pix though its proline rich region. This interaction is thought to affect the GTP hydrolysis rate of Rac and Cdc42.

免疫原

Epitope: SH3 domain
GST-tagged recombinant protein corresponding to the SH3 domain of human Beta-Pix, SH3 Domain.

应用

Western Blotting Analysis: 1 ?g/mL from a representative lot detected Beta-Pix, SH3 Domain in 10 ?g of PC-12 cell lysate.
Detect Beta Pix using this Anti-Beta Pix antibody, SH3 Domain validated for use in western blotting.
Research Category
Signaling
Research Sub Category
Signaling Neuroscience

质量

Evaluated by Western Blotting in Jurkat cell lysate.

Western Blotting Analysis: 0.2 ?g/mL of this antibody detected Beta-Pix, SH3 Domain in 10 ?g of Jurkat cell lysate.

目标描述

~80 kDa observed

联系

Replaces: 07-1450

外形

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Affinity purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss 32160702
NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
纯化方式 affinity chromatography
species reactivity human, rat, mouse
technique(s) western blot: suitable
NCBI登记号 NP_001106983
UniProt登记号 Q14155
运输 wet ice
Gene Information human ... ARHGEF7(8874)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

Sigma-Aldrich

推荐半岛bd体育手机客户端
Baidu
map