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Hepatitis C virus NS4 antigen-Rhodamine

品牌
Sigma-Aldrich
货号
H9784
规格纯度
~1 mg/mL, ≥95% (SDS-PAGE), recombinant, expressed inE. coli, solution
价格
6536.53 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
Hepatitis C virus NS4 antigen-Rhodamine
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

HCVgp1 (hepatitis C virus glycoprotein 1), also referred to as polyprotein, is crucial for the induction of double-membrane vesicles, which are sites of HCV RNA amplification. The amino terminal of polyprotein contains the structural proteins core, envelope protein 1 (E1) and E2. The proteolytic cleavage of polyprotein results in the formation of 10 mature viral proteins, including NS4 (non-structural 4).
β-gal fused at N-terminus

生化/生理作用

NS4 (non-structural 4) mainly acts a cofactor for the NS3 serine protease, which is needed for the cleavage of the non-structural area of the polyprotein. It also suppresses host cell translation as well as proliferation. In addition, it induces anti-inflammatory cytokines and thereby suppresses cellular immune responses.
Positive control for HCV antibodies.

其他说明

HCV NS4a+b [1658-1863]-Galactosidase-tagged, rhodamine conjugate.

外形

Solution in 8 M urea, 20 mM tris-HCl, pH 8.0, and 10 mM 2-mercaptoethanol.

基本信息

MDL编号 MFCD02264902
NACRES NA.32

半岛bd体育手机客户端 性质

质量水平 200
重组 expressed inE. coli
测定 ≥95% (SDS-PAGE)
形式 solution
分子量 19 kDa (plus 114 kDa β-Gal tag)
浓度 ~1 mg/mL
UniProt登记号 L7S4V3
运输 dry ice
储存温度 ?20℃
Gene Information hepatitis C virus ... HCVgp1(951475)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

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