FLT3 Ligand human

半岛bd体育手机客户端 说明

一般描述

Human FMS-like tyrosine kinase 3 (FLT3) ligand is a homodimer consisting of two short-chain α-helical bundles. The molecular weight of FLT3 ligand is 44 kDa.

包装

10 μg in poly bottle

生化/生理作用

FLT3 ligand binds to the cell-bound tyrosine kinase receptor and activates them.
HumanKine FLT3 Ligand is expressed in human HEK 293 cells as a glycosylated monomer with an apparent molecular mass of 24-30 kDa. HumanKine FLT3 Ligand in human HEK 293 cells contributes to glycosylation.FLT3 ligand is a hematopoietic cytokine that regulates the proliferation of early hematopoietic cells. It has been shown to synergize with a variety of cytokines to stimulate the growth and differentiation of early hematopoietic cells. The FLT3 ligand also stimulates the expansion of monocytes and immature dendritic cells, and induces early B cell lineage differentiation and NK cell growth.

外形

Lyophilized from a 0.2 μm filtered solution of 1x PBS.

分析说明

The specific activity was determined by the dose-dependent stimulation of the proliferation of the human acute myeloid leukemia cell line OCI-AML5.

法律信息

HumanKine is a registered trademark of Proteintech Group, Inc.

基本信息

MDL编号

MFCD01634859

半岛bd体育手机客户端 性质

质量水平	100
生物来源	human
重组	expressed in HEK 293 cells
测定	≥95% (SDS-PAGE)
形式	lyophilized powder
效能	≤0.8 ng/mL EC50
质量	endotoxin tested
分子量	monomer 24-30 kDa (glycosylated)
包装	pkg of 10 μg
储存条件	avoid repeated freeze/thaw cycles
technique(s)	cell culture | mammalian: suitable
杂质	≤1 EU/mg
储存温度	?20℃

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable