半岛bd体育手机客户端 说明
生化/生理作用
Growth factor ligand for ErbB3 and ErbB4 receptor tyrosine kinases. The binding of HRG results in receptor dimerization and receptor trans-autophosphorylation. The phosphorylated receptors recruit cellular signaling proteins, initiating signaling pathways.
分析说明
The biological activity is measured by its ability to stimulate the proliferation of human MCF-7 cells grown under serum-free conditions.
基本信息
MDL编号 | MFCD03457066 |
NACRES | NA.32 |
半岛bd体育手机客户端 性质
质量水平 | 200 |
生物来源 | human |
重组 | expressed inE. coli |
测定 | ≥98% (SDS-PAGE) |
形式 | lyophilized powder |
效能 | <0.50 ng/mL |
分子量 | predicted mol wt 8 kDa |
包装 | pkg of 10 and 50 μg |
储存条件 | avoid repeated freeze/thaw cycles |
杂质 | endotoxin, tested |
颜色 | white |
UniProt登记号 | Q02297 |
储存温度 | ?20℃ |
Gene Information | human ... NRG1(3084) |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
个人防护装备 | Eyeshields, Gloves, type N95 (US) |
Sigma-Aldrich