半岛bd体育手机客户端 说明

一般描述

Interleukin-4 (IL-4) is a pleiotropic cytokine and a complex glycoprotein mapped to human chromosome 5q31.1. It is produced by mast cells, basophils and a subset of activated T cells.

包装

10 μg in poly bottle

生化/生理作用

Interleukin-4 (IL-4) interacts with interleukin 13 and is an interleukin-4 receptor ligand. It regulates IgE and IgG1 production by B cells. IL-4 favors glial and neuronal differentiation and regulates differentiation of naive cluster of differentiation CD4⁺T cells to the T helper type 2 (TH2) cells. Polymorphism in the IL-4 gene is implicated in immune and inflammatory disorders. In cerebral infarction, IL-4 levels are elevated.

外形

Lyophilized from a 0.2 μm filtered solution of 1x PBS.

制备说明

HumanKine Interleukin-4 (IL-4), expressed in human HEK 293 cells, is a glycosylated monomer with an apparent molecular mass of 14-19 kDa due to glycosylation, which is absent when this cytokine is expressed inE. coli.Production in human HEK 293 cells offers authentic glycosylation. Glycosylation contributes to stability in cell growth media and other applications.

分析说明

The specific activity was determined by the dose-dependent simulation of the proliferation of human TF-1 cells (human erythroleukemic indicator cell line).

法律信息

HumanKine is a registered trademark of Proteintech Group, Inc.

基本信息

MDL编号	MFCD00151705
NACRES	NA.77

半岛bd体育手机客户端 性质

质量水平	100
生物来源	human
重组	expressed in HEK 293 cells
测定	>95% (SDS-PAGE)
形式	lyophilized powder
效能	≤0.6 ng/mL EC50
质量	endotoxin tested
分子量	dimer 14-19 kDa (glycosylated)
包装	pkg of 1 mg pkg of 10 μg pkg of 100 μg
manufacturer/tradename	HumanZyme
technique(s)	cell culture | mammalian: suitable
杂质	<1 EU/μg
UniProt登记号	P05112
储存温度	?20℃
Gene Information	human ... IL4(3565)

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable