半岛bd体育手机客户端 说明
一般描述
Relatively selective blocker of L-type Ca2+channels. One of the most extensively studied blockers of 1,4-dihydropyridine-type Ca2+channels, and a pharmacologically-useful vasodilator. Induces apoptosis in human glioblastoma cells.
Relatively selective blocker of L-type Ca2+channels. One of the most extensively studied Ca2+channel blockers of 1,4-dihydropyridine-type and a pharmacologically useful vasodilator. Induces apoptosis in human glioblastoma cells.
包装
250 mg in Plastic ampoule
生化/生理作用
Product does not compete with ATP.
Reversible: no
Primary Target
L-type Ca2+ channels
Cell permeable: no
警告
Toxicity: Harmful & Carcinogenic / Teratogenic (E)
重悬
Following reconstitution, refrigerate (-20°C). Stock solutions are stable for up to 3 months at -20°C.
其他说明
Reid, K., et al. 1997.J. Pharmacol. Exp. Ther.283,993.
Kondo, S., et al. 1995.J. Neurosurg.82,469.
Antkiewicz-Michaluk, L., et al. 1994.Eur. J. Pharmacol.254,9.
Calabresi, P., et al. 1994.J. Neurosci.14,4871.
Akman, M.S., et al. 1993.Endocrinology132,1286.
Cirillo, M., et al. 1993.Circ. Res.72,847.
Young, R.J., et al. 1993.Biochim. Biophys. Acta1146,81.
Janis, R., et al. 1987.Adv. Drug Res.16,311.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
基本信息
| 经验(实验)分子式 | C17H18N2O6 |
| 分子量 | 346.33 |
| MDL编号 | MFCD00057326 |
半岛bd体育手机客户端 性质
| 质量水平 | 100 |
| 测定 | ≥98% (UV) |
| 形式 | solid |
| manufacturer/tradename | Calbiochem? |
| 储存条件 | OK to freeze protect from light |
| 颜色 | yellow |
| 溶解性 | DMSO: soluble ethanol: soluble |
| 运输 | ambient |
| 储存温度 | 10-30℃ |
| InChI | 1S/C17H18N2O6/c1-9-13(16(20)24-3)15(14(10(2)18-9)17(21)25-4)11-7-5-6-8-12(11)19(22)23/h5-8,15,18H,1-4H3 |
| InChI key | HYIMSNHJOBLJNT-UHFFFAOYSA-N |
安全信息
| 象形图 |  |
| 警示用语： | Warning |
| 危险声明 | H302 |
| 预防措施声明 | P264 - P270 - P301 + P312 - P501 |
| 危险分类 | Acute Tox. 4 Oral |
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
