您好,欢迎来到半岛电竞官方网址 ! [ 登录] [ 免费注册]
半岛电竞官方网址
位置: 首页> 品牌> Sigma-Aldrich> Chlorpromazine, Hydrochloride-CAS 69-09-0-Calbiochem

Chlorpromazine, Hydrochloride-CAS 69-09-0-Calbiochem

品牌
Sigma-Aldrich
CAS
69-09-0
货号
215921
规格纯度
Inhibits calmodulin-dependent stimulation of cyclic nucleotide phosphodiesterase (IC50= 17 μM).
价格
1364.79 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
- +
半岛bd体育手机客户端 名称:
69-09-0
Chlorpromazine, Hydrochloride-CAS 69-09-0-Calbiochem
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Inhibits calmodulin-dependent stimulation of cyclic nucleotide phosphodiesterase (IC50= 17 ?M). Acts as a peripheral vasodilator. An inhibitor of TNFα production. Inhibits nitric oxide synthase (NOS) in mouse brain and prevents lipopolysaccharide induction of NOS in murine lung. Shown to potently and specifically inhibit KSP/Eg5 (IC50<10 ?M), and PLA2.
Inhibits calmodulin-dependent stimulation of cyclic nucleotide phosphodiesterase (IC?? = 17 ?M).
Inhibits calmodulin-dependent stimulation of cyclic nucleotide phosphodiesterase (IC50= 17 ?M). Acts as a peripheral vasodilator. Acts as an inhibitor of lysosomal sphingomyelinase and of TNF-α production. Inhibits nitric oxide synthase (NOS) in mouse brain and prevents lipopolysaccharide induction of NOS in murine lung. Shown to potently and specifically inhibit KSP/Eg5 (IC50<10 ?M), and PLA2.

包装

500 mg in Alu drum

生化/生理作用

Product does not compete with ATP.
Primary Target
Calmodulin-dependent stimulation of cyclic nucleotide phosphodiesterase
Target IC50: 17 ?M inhibiting calmodulin-dependent stimulation of cyclic nucleotide phosphodiesterase

警告

Toxicity: Toxic (F)

重悬

Following reconstitution, aliquot and freeze at -20°C. Stock solutions are stable for up to 6 months at -20°C and for up to 1 week at 4°C.

其他说明

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Lee, M.S., et al. 2007.Cancer Res.67,11359.
Maor, I., et al. 1995.Arteriosclero. Thromb. Vasc. Biol.15,1378.
Netea, M.G., et al. 1995.J. Infect. Dis.171,393.
Lindahl, M., and Tagesson, C. 1993.Inflammation17,573.
Palacios, M., et al. 1993.Biochem. Biophys. Res. Commun.196,280.
Yamamoto, H. 1993.Toxicol. Lett.66,73.
Vadas, P., et al. 1986.Agents Actions19,194.
Marshak, P.R., et al. 1985.Biochemistry24,144.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式 C17H19ClN2S · xHCl
分子量 318.86 (free base basis)
MDL编号 MFCD00012654

半岛bd体育手机客户端 性质

质量水平 100
测定 ≥99% (HPLC)
形式 crystalline solid
manufacturer/tradename Calbiochem?
储存条件 OK to freeze
desiccated (hygroscopic)
颜色 off-white
溶解性 methanol: 10 mg/mL
water: 50 mg/mL
痕量阴离子 sulfate (SO42-): ≤0.05%
痕量阳离子 Fe: ≤0.001%
heavy metals: ≤0.002%
运输 ambient
储存温度 10-30℃
InChI 1S/C17H19ClN2S.ClH/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20;/h3-4,6-9,12H,5,10-11H2,1-2H3;1H
InChI key FBSMERQALIEGJT-UHFFFAOYSA-N

安全信息

象形图 GHS06
警示用语: Danger
危险声明 H301 - H330
预防措施声明 P260 - P264 - P270 - P271 - P284 - P304 + P340 + P310
危险分类 Acute Tox. 1 Inhalation - Acute Tox. 3 Oral
储存分类代码 6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

Sigma-Aldrich

推荐半岛bd体育手机客户端
Baidu
map