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位置: 首页> 品牌> Sigma-Aldrich> Poly(ethylene glycol) methyl ether-block-poly(lactide-co-glycolide)

Poly(ethylene glycol) methyl ether-block-poly(lactide-co-glycolide)

品牌
Sigma-Aldrich
货号
911410
规格纯度
PEG average Mn5,000, PLGA average Mn10,000, lactide:glycolide 80:20
价格
2841.92 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
Poly(ethylene glycol) methyl ether- block-poly(lactide- co-glycolide)
PEG-PLGA
mPEG- b-PLGA
PEG5K-PLGA10K
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

应用

This polymer is a amphiphilic diblock copolymer composed of a hydrophilic PEGblockand a hydrophobic PLGAblock. This biodegradable, biocompatible polymers can self-assemble to form nanoparticles, such as micelles and polymersomes, in both aqueous and non-aqueous media. Due to these properties, these polymers are widely used in polymeric nanoparticle formulation to achieve controlled and targeted delivery of therapeutic agents (e.g. APIs, genetic material, peptides, vaccines, and antibiotics). Additionally, well-defined nanoparticles with tunable size and properties can be prepared by altering the molecular weight ratios between hydrophilic and hydrophobic blocks, as well as by controlling formulation parameters.

基本信息

线性分子式 H[(C3H4O2)x(C2H2O2)y]mO[C2H4O]nCH3

半岛bd体育手机客户端 性质

形式 powder
投料比 lactide:glycolide 80:20
分子量 PEG average Mn5,000 (by NMR)
PLGA average Mn10,000 (by NMR)
杂质 ≤500 ppm (GC)
颜色 white
储存温度 ?20℃

安全信息

储存分类代码 11 - Combustible Solids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

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