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位置: 首页> 品牌> Sigma-Aldrich> Anti-Glutamate Receptor 6, Metabotropic antibody produced in rabbit

Anti-Glutamate Receptor 6, Metabotropic antibody produced in rabbit

品牌
Sigma-Aldrich
货号
G1795
规格纯度
affinity isolated antibody, buffered aqueous solution
价格
4330.86 *本价格含增值税费
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半岛bd体育手机客户端 名称:
Anti-Glutamate Receptor 6, Metabotropic antibody produced in rabbit
Anti-MGLUR6
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

免疫原

synthetic peptide corresponding to the N-terminal extracellualr domain of human metabotropic glutamate receptor 6, conjugated to KLH. The immunizing peptide has 100% homology with the rat and mouse gene.

应用

Anti-Glutamate Receptor 6, Metabotropic antibody is suitable for immunohistochemistry (formalin-fixed, paraffin-embedded sections) at a concentration of 12μg/mL using human ganglion layer, retina.

生化/生理作用

Glutamate, the excitatory neurotransmitter, is involved in fast excitatory synaptic transmission. It acts on ligand-gated receptor channels, termed NMDA, AMPA and kainate receptors. The metabotropic form consist of eight subtypes (mGluR1-8) divided into three groups (I-III). Group I binds to phospholipase C and intracellular calcium mobilization, whereas both groups II and III inhibit adenyl cyclase. The metabotropic receptors have some therapeutic potentials. group I receptors have been implicated in post-ischemic neuronal injury, and antagonists of group I appear to have a neuroprotective effect.

外形

Solution in phosphate buffered saline, pH 7.7, containing 0.01% sodium azide.

基本信息

MDL编号 MFCD03097014
NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 200
偶联物 unconjugated
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
species reactivity human
availability not available in Japan
technique(s) immunohistochemistry (formalin-fixed, paraffin-embedded sections): 12 μg/mL using human ganglion layer, retina
UniProt登记号 O15303
运输 dry ice
储存温度 ?20℃
Gene Information human ... GRM6(2916)
mouse ... Grm6(108072)
rat ... Grm6(24419)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK nwg
闪点(F) Not applicable
闪点(C) Not applicable

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