Anti-phospho-Growth Associated Protein-43 (pSer⁴¹) antibody produced in rabbit

半岛bd体育手机客户端 说明

免疫原

synthetic phosphopeptide derived from the region of rat GAP-43 phosphorylated on serine 41.

应用

Anti-phospho-Growth Associated Protein-43 (pSer41) antibody produced in rabbit is suitable for immunoblotting at a working dilution of 1:1000.

生化/生理作用

GAP-43 is an intracellular phosphoprotein that is present exclusively in the peripheral and central nervous systems. Protein kinase C (PKC) phosphorylates GAP-43 on a single site, serine 41. This phosphorylated protein is found in the areas where growth cones make productive and stable contacts with other cells. It facilitates stabilization of long actin filaments. Phosphorylation by PKC at serine 41 is related to nerve-terminal sprouting and long-term potentiation as high levels of GAP-43 are present in neocortical areas and in the limbic system. It is crucial in mediating experience dependent plasticity.

外形

Solution in 10 mM HEPES, pH 7.5, containing 150 mM NaCl, 100 μg/mL BSA, and 50% glycerol.

分析说明

An additional band at 150-160 kDa may be detected and reflects the oligomeric nature of GAP-43.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号	MFCD03791562
NACRES	NA.41

半岛bd体育手机客户端 性质

生物来源	rabbit
质量水平	200
偶联物	unconjugated
抗体形式	affinity isolated antibody
antibody product type	primary antibodies
克隆	polyclonal
形式	buffered aqueous solution
分子量	antigen 43 kDa
species reactivity	rat, human, mouse
technique(s)	western blot: 1:1,000
UniProt登记号	P17677
运输	dry ice
储存温度	?20℃
Gene Information	human ... GAP43(2596) mouse ... Gap43(14432) rat ... Gap43(29423)

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 2
闪点(F)	Not applicable
闪点(C)	Not applicable