Anti-Glutamate Receptor NMDAR1 (NR1) (Splice Variant Insert C1) antibody produced in rabbit

半岛bd体育手机客户端 说明

免疫原

synthetic peptide representing the sequence of the C1 splice variant.

应用

Anti-Glutamate Receptor NMDAR1 (NR1) (Splice Variant Insert C1) antibody is suitable for immunohistochemistry (frozen sections) at a dilution of 1:1000-1:2000 and western blot at 1:1000 dilution using rat and mouse tissue.

生化/生理作用

NMDA receptors (NMDAR) are glutamate-gated ion channels. It is sensitive to N-methyl-D-aspartate (NMDA) and consists of several homologous subunits (NMDAR1). NMDAR is highly expressed in the central nervous system and involved in excitatory synaptic transmission as well as synaptic plasticity. The activity of NMDA receptors are modulated by glycine. It exhibits high calcium permeability and unique voltage-dependent sensitivity to magnesium. It has been reported that phosphorylated NMDA receptors may regulate their function and play a role in many forms of synaptic plasticity such as long-term potentiation.

外形

Lyophilized powder from 5 mM ammonium bicarbonate, so some residual salt may be present

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号	MFCD02096426
NACRES	NA.41

半岛bd体育手机客户端 性质

生物来源	rabbit
质量水平	100
偶联物	unconjugated
抗体形式	affinity isolated antibody
antibody product type	primary antibodies
克隆	polyclonal
形式	lyophilized powder
分子量	antigen 100 kDa
species reactivity	rat, mouse
包装	antibody small pack of 25 μg
technique(s)	immunohistochemistry (frozen sections): 1:1000-1:2000 western blot: 1:1000 using rat and mouse tissue
UniProt登记号	P35439
储存温度	2-8℃
Gene Information	mouse ... Grin1(14810) rat ... Grin1(24408)

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable