GW2974

半岛bd体育手机客户端 说明

包装

50, 250 mg in glass bottle

生化/生理作用

Potent and selective dual inhibitor of EGFR (IC₅₀= 0.016 mM) and ErbB-2 receptor tyrosine kinase.

特点和优势

This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

法律信息

Sold for research purposes under agreement from GlaxoSmithKline

基本信息

经验(实验)分子式	C23H21N7
分子量	395.46
MDL编号	MFCD04974495
PubChem化学物质编号	24278451
NACRES	NA.77

半岛bd体育手机客户端 性质

质量水平	100
测定	≥98% (HPLC)
形式	solid
颜色	yellow
溶解性	DMSO: ≥20 mg/mL
创始人	GlaxoSmithKline
SMILES string	CN(C)c1cc2c(Nc3ccc4n(Cc5ccccc5)ncc4c3)ncnc2cn1
InChI	1S/C23H21N7/c1-29(2)22-11-19-20(13-24-22)25-15-26-23(19)28-18-8-9-21-17(10-18)12-27-30(21)14-16-6-4-3-5-7-16/h3-13,15H,14H2,1-2H3,(H,25,26,28)
InChI key	DYYZXRCFCVDSKD-UHFFFAOYSA-N
Gene Information	human ... EGFR(1956), ERBB2(2064)

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, type N95 (US)