半岛bd体育手机客户端 说明

应用

GR 103691 has been used as a D3 receptor antagonist to test its:

• inducing effect on prepulse inhibition (PPI)
• suppressive effect of motor behavior in rats
• inhibitory effect on chemotaxis in newly excysted juvenileC. sinensis(CsNEJs)

包装

10 mg in glass bottle

生化/生理作用

GR 103691 increases the monosynaptic “stretch” reflex (MSR) amplitude in mice by its potent D3 receptor antagonist functionality. It inhibits the PD 128,907 mediated γ-aminobutyric acid (GABA) release.
D₃dopamine receptor antagonist.

特点和优势

This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
This compound is featured on the Dopamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

法律信息

Sold for research purposes under agreement from GlaxoSmithKline

基本信息

经验(实验)分子式	C30H35N3O3
分子量	485.62
MDL编号	MFCD00936840
PubChem化学物质编号	24724488
NACRES	NA.77

半岛bd体育手机客户端 性质

质量水平	100
测定	≥98% (HPLC)
形式	solid
颜色	white
溶解性	DMSO: soluble >5 mg/mL at 60 ℃
创始人	GlaxoSmithKline
储存温度	2-8℃
SMILES string	COc1ccccc1N2CCN(CCCCNC(=O)c3ccc(cc3)-c4ccc(cc4)C(C)=O)CC2
InChI	1S/C30H35N3O3/c1-23(34)24-9-11-25(12-10-24)26-13-15-27(16-14-26)30(35)31-17-5-6-18-32-19-21-33(22-20-32)28-7-3-4-8-29(28)36-2/h3-4,7-16H,5-6,17-22H2,1-2H3,(H,31,35)
InChI key	JARNORYOPMINDY-UHFFFAOYSA-N
Gene Information	rat ... Htr1a(24473)

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, type N95 (US)