半岛bd体育手机客户端 说明
一般描述
Corosolic acid fromLagerstroemia speciosais a pentacyclic triterpenoid found in a variety of plants, such as apples, basil, bilberries, cranberries, and prunes. It is a natural derivative of ursolic acid.
应用
Corosolic acid fromLagerstroemia speciosahas been used to study the inhibiting activity of ursolic acid and its derivative against colon cancer cells by causing degradation of β-catenins.
包装
10 mg in glass bottle
50 mg in poly bottle
生化/生理作用
Corosolic acid fromLagerstroemia specioseshows a variety of biological activities such as anti-proliferation, apoptosis, and anti-carcinogenic. It exhibits an inhibiting effect on the post-challenge plasma glucose levels in humans. Corosolic acid, due to its ability to improve glucose metabolism, has been touted to be used in the management of Type-2 Diabetes. It improves hypertension, oxidative stress, and inflammation, thereby being a potential candidate to be used against atherosclerosis-related diseases.
Triterpene phytochemical found in medicinal herbal extracts. Possesses antiatherosclerotic, antihyperlipidemic, antioxidant, antiinflammatory, antifungal, antiviral and antineoplastic activities.
基本信息
经验(实验)分子式 | C30H48O4 |
分子量 | 472.70 |
MDL编号 | MFCD06794973 |
PubChem化学物质编号 | 329799816 |
NACRES | NA.25 |
半岛bd体育手机客户端 性质
质量水平 | 200 |
测定 | ≥98% (HPLC) |
形式 | powder |
溶解性 | methanol: 1 mg/mL, clear, colorless |
储存温度 | 2-8℃ |
SMILES string | O[C@H]1[C@H](O)C(C)(C)[C@@](CC[C@]2(C)[C@]3([H])CC=C4[C@@]2(C)CC[C@]5(C(O)=O)[C@@]4([H])[C@@H](C)[C@H](C)CC5)([H])[C@]3(C)C1 |
InChI | 1S/C30H48O4/c1-17-10-13-30(25(33)34)15-14-28(6)19(23(30)18(17)2)8-9-22-27(5)16-20(31)24(32)26(3,4)21(27)11-12-29(22,28)7/h8,17-18,20-24,31-32H,9-16H2,1-7H3,(H,33,34)/t17-,18+,20-,21+,22-,23+,24+,27+,28-,29-,30+/m1/s1 |
InChI key | HFGSQOYIOKBQOW-ZSDYHTTISA-N |
安全信息
储存分类代码 | 11 - Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich