半岛bd体育手机客户端 说明

应用

Fenoldopam mesylate may be used to study dopamine D₁-mediated cell signaling.

包装

10, 50 mg in glass bottle

生化/生理作用

Fenoldopam mesylate (FM) is considered as an effective therapeutic agent to prevent the onset of postoperative AKI (PO-AKI). In healthy cats, FM can stimulate diuresis and be well-tolerated. This benzazepine-derivative is regional specific and does not cause cerebral vasodilation.
Fenoldopam mesylate is a selective dopamine D₁receptor agonist used as an antihypertensive agent. It is an agonist for D₁-like dopamine receptors and binds with moderate affinity to α2-adrenoceptors. It has no significant affinity for D₂-like receptors, α1 and α-adrenoceptors, 5HT₁and 5HT₂receptors, or muscarinic receptors. Fenoldopam mesylate causes peripheral vasodilation by stimulating dopamine-1receptors and α2-adrenoceptors, increasing renal blood flow.

特点和优势

This compound is featured on the Dopamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

基本信息

经验(实验)分子式	C16H16ClNO3· CH4O3S
分子量	401.86
EC 号	266-612-7
MDL编号	MFCD04112986
PubChem化学物质编号	329825223
NACRES	NA.77

半岛bd体育手机客户端 性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
储存条件	desiccated
颜色	white to tan
mp	271 ℃ (lit.)
溶解性	DMSO: ≥15 mg/mL at ~60 ℃
储存温度	room temp
SMILES string	CS(O)(=O)=O.Oc1ccc(cc1)C2CNCCc3c(Cl)c(O)c(O)cc23
InChI	1S/C16H16ClNO3.CH4O3S/c17-15-11-5-6-18-8-13(9-1-3-10(19)4-2-9)12(11)7-14(20)16(15)21;1-5(2,3)4/h1-4,7,13,18-21H,5-6,8H2;1H3,(H,2,3,4)
InChI key	CVKUMNRCIJMVAR-UHFFFAOYSA-N
Gene Information	human ... DRD1(1812)

安全信息

象形图
警示用语：	Warning
危险声明	H302 - H317 - H319
预防措施声明	P280 - P301 + P312 + P330 - P302 + P352 - P305 + P351 + P338
危险分类	Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Sens. 1
储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable