Anti-HDL antibody produced in chicken

半岛bd体育手机客户端 说明

免疫原

HDL human native protein.

应用

Anti-HDL antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

生化/生理作用

11β-hydroxysteroid dehydrogenase type 1 is an NADPH-dependent enzyme highly expressed in metabolic tissues that include liver, adipose tissue and the central nervous system. It may contribute to the loss of muscle strength with age and is a key component of sarcopenia. Inhibition of HDL gene may have some therapeutic potential in sarcopenia. HDL gene variation may affect the physiological cortisol levels and the severity of age-related osteoporosis. It is involved in regenerating active glucocorticoids, that are selectively elevated in adipose tissue in human obesity and metabolic syndrome, both associated with chronic low-grade inflammation. HDL acts as an oxidoreductase to yield active glucocorticoids, cortisol or corticosterone. It is expressed in normal human epidermal keratinocytes (NHEKs) and negatively regulates proliferation of NHEKs.

外形

Solution in phosphate buffered saline containing 0.02% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号	MFCD00162396
NACRES	NA.41

半岛bd体育手机客户端 性质

生物来源	chicken
质量水平	200
偶联物	unconjugated
抗体形式	affinity isolated antibody
antibody product type	primary antibodies
克隆	polyclonal
形式	buffered aqueous solution
species reactivity	human
manufacturer/tradename	Genway 15-288-20088F
technique(s)	western blot: suitable
UniProt登记号	P28845
运输	wet ice
储存温度	?20℃
Gene Information	human ... HSD11B1(3290)

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)