Anti-GIPC1 antibody produced in chicken

半岛bd体育手机客户端 说明

免疫原

Recombinant regulator of G-protein signalling 19 interacting protein 1 isoform 1
Immunogen Sequence: GI # 5031715, sequence 1-333

应用

Anti-GIPC1 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

生化/生理作用

GIPC PDZ domain containing family, member 1 (GIPC1) is a protein encoded by the GIPC1 gene in humans. The mammalian GIPC1 consists of a central PDZ domain and a C-terminal acyl carrier protein (ACP) domain. It is an essential adaptor protein of receptors that plays an important role in cancer progression and therapy resistance. The GIPC1 cytoplasmic scaffold protein interacts with numerous receptor signaling complexes and plays a role in tumorigenesis. It is highly expressed in a number of human malignancies that include breast, ovarian, gastric and pancreatic cancers. GIPC1 inhibition may be a new target for therapeutic development for the treatment of human cancers. It is a breast cancer-associated immunogenic antigen that is overexpressed in breast cancer.

外形

Solution in phosphate buffered saline containing 0.02% sodium azide.

基本信息

NACRES

NA.41

半岛bd体育手机客户端 性质

生物来源	chicken
质量水平	200
偶联物	unconjugated
抗体形式	affinity isolated antibody
antibody product type	primary antibodies
克隆	polyclonal
形式	buffered aqueous solution
species reactivity	human, mouse, rat
manufacturer/tradename	Genway 15-288-22308F
technique(s)	western blot: suitable
NCBI登记号	NP_005707.1
UniProt登记号	O14908
运输	wet ice
储存温度	?20℃
Gene Information	human ... GIPC1(10755)

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)