Anti-Human Kappa Light Chain antibody produced in chicken

半岛bd体育手机客户端 说明

免疫原

Human IgK (Kappa) native protein.

应用

Anti-Human Kappa Light Chain antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

生化/生理作用

Immunoglobulin κ constant (IGKC) is a human gene that encodes the constant domain of κ-type light chains for antibodies. It is found on chromosome 2 in humans. IGKC acts as a strong prognostic marker in several human solid tumors, including breast cancer. Its expression may have a role for humoral immunity in breast cancer progression. IGKC is also found to be expressed in non-small lung cancer (NSCLC) and may act as a prognostic marker in NSCLC, supporting emerging treatment concepts that exploit the humoral immune response. Its has an independent protective impact on disease-free survival (DFS) and breast cancer-specific overall survival in node-negative breast cancer. IGKC acts as a novel diagnostic marker for risk stratification in human cancer and may help to exploit the humoral immune response for anticancer therapy.

外形

Solution in phosphate buffered saline containing 0.02% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号

MFCD00162517

半岛bd体育手机客户端 性质

生物来源	chicken
质量水平	200
偶联物	unconjugated
抗体形式	affinity isolated antibody
antibody product type	primary antibodies
克隆	polyclonal
形式	buffered aqueous solution
species reactivity	human
manufacturer/tradename	Genway 15-288-20087F
technique(s)	western blot: suitable
UniProt登记号	P01834
运输	wet ice
储存温度	?20℃
Gene Information	human ... IGKC(3514)

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)