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Anti-Fatty Acid Synthase (C-terminal) antibody produced in rabbit

品牌
Sigma-Aldrich
货号
F9679
规格纯度
1 mg/mL, affinity isolated antibody, buffered aqueous solution
价格
4731.57 *本价格含增值税费
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数量
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半岛bd体育手机客户端 名称:
Anti-Fatty Acid Synthase (C-terminal) antibody produced in rabbit
Anti-FASN
Anti-FAS
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Fatty acid synthase (FAS, FASN) is a multifunctional protein, mainly involved in catalyzing the synthesis of palmitate from acetyl-CoA and malonyl CoA, in the presence of NADPH. In mammals, it is composed of two identical multifunctional polypeptides, in which three catalytic domains in the N-terminal section (β-ketoacyl synthase, malonyl/acetyl tansferase, and dehydrase) are separated by a core region of about 600 residues from four C-terminal domains (enoyl reductase, β-ketoacyl reductase, acyl carrier protein, and thioesterase).

免疫原

synthetic peptide corresponding to amino acids 2497-2511 of human fatty acid synthase, conjugated to KLH via an N-terminal added lysine residue. The corresponding sequence is conserved in human, rat, and mouse.

应用

Anti-Fatty Acid Synthase (C-Terminal) antibody is suitable for western blot analysis at a concentration of 0.5-1μg/mL using lysates of Rat1 cells and 1-2μg/mL using lysates of human HEK 293-T cells.

生化/生理作用

FAS plays an essential role during embryogenesis and energy homeostasis in adult animals. It also acts as the carbon source for fatty acid synthesis. It has been shown to be overexpressed in various types of human cancer, including prostate, breast, ovary and others.

外形

0.01M 磷酸缓冲盐溶液,pH 7.4,含 15mM 叠氮化钠。

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号 MFCD00283209
NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 200
偶联物 unconjugated
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
分子量 antigen 270 kDa
species reactivity mouse, rat, human
浓度 1 mg/mL
technique(s) western blot: 0.5-1 μg/mL using lysates of Rat1 cells
western blot: 1-2 μg/mL using lysates of human HEK 293-T cells
UniProt登记号 P49327
运输 dry ice
储存温度 ?20℃
Gene Information human ... FASN(2194)
mouse ... Fasn(14104)
rat ... Fasn(50671)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable
个人防护装备 Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Sigma-Aldrich

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