半岛bd体育手机客户端 说明
应用
Fluspirilene has been used as a neuroleptic drug to study its effects on human ether-a-go-go related gene (HERG).
Fluspirilene has been used to study its cytotoxicity effect on malignant glioma.
包装
10, 50 mg in glass bottle
生化/生理作用
Fluspirilene has a potential to inhibit the activity of cyclin-dependent kinase 2 (CDK2). It is an effective anti-cancer agent used for treating human hepatocellular carcinoma.
Fluspirilene is a dopamine receptor antagonist. It also acts as a calcium channel blocker. Fluspirilene is an antipsychotic agent and exhibits neuoleptic properties. It exhibits therapeutic effects against glioblastoma and Schizophrenia.
特点和优势
This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
基本信息
| 经验(实验)分子式 | C29H31F2N3O |
| 分子量 | 475.57 |
| EC 号 | 217-418-6 |
| MDL编号 | MFCD00055137 |
| PubChem化学物质编号 | 24277915 |
| NACRES | NA.77 |
半岛bd体育手机客户端 性质
| 测定 | ≥98% (HPLC) |
| 形式 | solid |
| 颜色 | white |
| 溶解性 | DMSO: ≥20 mg/mL H2O: insoluble ethanol: soluble |
| 创始人 | Johnson & Johnson |
| 储存温度 | room temp |
| SMILES string | Fc1ccc(cc1)C(CCCN2CCC3(CC2)N(CNC3=O)c4ccccc4)c5ccc(F)cc5 |
| InChI | 1S/C29H31F2N3O/c30-24-12-8-22(9-13-24)27(23-10-14-25(31)15-11-23)7-4-18-33-19-16-29(17-20-33)28(35)32-21-34(29)26-5-2-1-3-6-26/h1-3,5-6,8-15,27H,4,7,16-21H2,(H,32,35) |
| InChI key | QOYHHIBFXOOADH-UHFFFAOYSA-N |
| Gene Information | human ... DRD1(1812), DRD2(1813), DRD3(1814), DRD4(1815), DRD5(1816) |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, type N95 (US) |
Sigma-Aldrich
m.cnreagent.com
