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Etidronate disodium hydrate

依替膦酸钠 二钠 水合物

品牌
Sigma-Aldrich
CAS
7414-83-7
货号
P5248
规格纯度
≥97% (NMR), solid
价格
1156.54 *本价格含增值税费
促销
服务
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数量
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半岛bd体育手机客户端 名称:
7414-83-7
Etidronate disodium hydrate
Dihydrogen (1-hydroxyethylidene)bisphosphonate disodium hydrate
依替膦酸钠 二钠 水合物
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

应用

Etidronate disodium hydrate has been used in the synthesis of bisphosphonate derivatives of adenosine triphosphate (ATP)by T4 RNA ligase. It has also been sued to inhibit human farnesyl diphosphate synthase (FDPS).

包装

10, 100 mg in glass bottle

生化/生理作用

Etidronate helps to guard chronic ocular hypertension prompted retinal oxidative stress. It stimulates the development of retinal ganglion cells through insulin-like growth factor 1 (IGF-1) signaling pathway. It may possess neuroprotective effects inin vivoandin vitrorat model of glaucoma. Etidronate belongs to bisphosphonates.
Bisphosphonate antiresorptive agent. Less potent inhibitor of farnesyl diphosphate synthase (IC50= 80 μM) as compared to the nitrogen containing bisphosphonates

基本信息

经验(实验)分子式 C2H6Na2O7P2· xH2O
分子量 249.99 (anhydrous basis)
EC 号 231-025-7
MDL编号 MFCD00152567
PubChem化学物质编号 329820220
NACRES NA.77

半岛bd体育手机客户端 性质

质量水平 100
测定 ≥97% (NMR)
形式 solid
颜色 white
mp >300 ℃
溶解性 H2O: ≥10 mg/mL
储存温度 2-8℃
SMILES string [Na+].[Na+].CC(O)(P(O)([O-])=O)P(O)([O-])=O
InChI 1S/C2H8O7P2.2Na/c1-2(3,10(4,5)6)11(7,8)9;;/h3H,1H3,(H2,4,5,6)(H2,7,8,9);;/q;2*+1/p-2
InChI key GWBBVOVXJZATQQ-UHFFFAOYSA-L

安全信息

象形图 GHS07
警示用语: Warning
危险声明 H302
危险分类 Acute Tox. 4 Oral
储存分类代码 13 - Non Combustible Solids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable
个人防护装备 dust mask type N95 (US), Eyeshields, Gloves

Sigma-Aldrich

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