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位置: 首页> 品牌> Sigma-Aldrich> Anti-CD3 (human), PerCP, clone SK7 Antibody

Anti-CD3 (human), PerCP, clone SK7 Antibody

品牌
Sigma-Aldrich
货号
MABF173E
规格纯度
clone SK7, from mouse, Peridinin-Chlorophyll-Protein Complex
价格
7533.38 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
Anti-CD3 (human), PerCP, clone SK7 Antibody
T-cell surface glycoprotein CD3 epsilon chain, T-cell surface antigen T3/Leu-4 epsilon chain, CD antigen CD3e, CD3
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

The SK7 antibody is specific for human CD3e, also known as CD3 epsilon, a 20 kDa subunit of the T cell receptor complex, along with CD3 gamma and CD3 delta. These integral membrane protein chains assemble with additional chains of the T cell receptor (TCR), as well as CD3 zeta chain, to form the T cell receptor – CD3 complex. Together with co-receptors CD4 or CD8, the complex serves to recognize antigens bound to MHC molecules on antigen-presenting cells. These interactions promote T cell receptor signaling (T cell activation), inducing cell proliferation, differentiation, production of cytokines or activation-induced cell death. CD3 is differentially expressed during thymocyte-to-T cell development and on all mature T cells.The SK7 antibody is a widely used phenotypic marker for human T cells. This antibody may induce T cell activation in the presence of monocytes. The antibody has also been demonstrated to be cross-reactive with Chimpanzee CD3. Binding of clone SK7 can be blocked by an alternative Anti-Human CD3 clone, OKT3. Please choose the appropriate format for each application.

免疫原

Immunogen information for this antibody is proprietary information.

应用

Research Sub Category
Immunoglobulins & Immunology
Anti-CD3 (human), PerCP, clone SK7 Antibody is an antibody against CD3 for use in Flow Cytometry.
Research Category
Inflammation & Immunology

质量

This monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation.

Flow Cytometry Analysis: 0.25 μg from a representative lot detected CD3 in one million human peripheral blood lymphocytes.

外形

Purified Mouse monoclonal containing 10 mM NaH2PO4, 150 mM NaCl, 0.09% NaN3, 0.1% gelatin, pH7.2.
Purified by size-exclusion chromatography

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.
Note: It is recommended to store the product undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze.

其他说明

Concentration: Please refer to lot specific datasheet.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss 32160702
NACRES NA.41

半岛bd体育手机客户端 性质

质量水平 100
生物来源 mouse
偶联物 Peridinin-Chlorophyll-Protein Complex
抗体形式 purified antibody
antibody product type primary antibodies
克隆 SK7, monoclonal
species reactivity human
technique(s) flow cytometry: suitable
UniProt登记号 P07766
Gene Information human ... CD3E(916)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK nwg
闪点(F) Not applicable
闪点(C) Not applicable

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